2020
DOI: 10.1016/j.etap.2020.103385
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Acute toxic effects of lead (Pb2+) exposure to rare minnow (Gobiocypris rarus) revealed by histopathological examination and transcriptome analysis

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Cited by 26 publications
(12 citation statements)
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“…Y21201-1-101), and all experiments were conducted as per the guidelines of the committee. The Pb 2+ treatment and LC 50 assessment were performed as described previously ( 57 ).…”
Section: Methodsmentioning
confidence: 99%
“…Y21201-1-101), and all experiments were conducted as per the guidelines of the committee. The Pb 2+ treatment and LC 50 assessment were performed as described previously ( 57 ).…”
Section: Methodsmentioning
confidence: 99%
“…In the control groups, the same volume of PBS was added. One hundred millilitre water from the middle of the aquarium and the posterior intestine of grass carp from each aquarium were sampled ( n = 3) at 6 h, 48 h and 96 h (W6 h, W48 h, W96 h, C6 h, C48 h and C96 h, respectively) after Pb(NO 3 ) 2 or PBS exposure (Liu et al, 2020; Shi et al, 2020; Souid et al, 2015). Fish were not fed during the 96 h of Pb exposure.…”
Section: Methodsmentioning
confidence: 99%
“…[55][56][57][58] Together with brain damage, lead also induces kidney damage, gastrointestinal diseases, high blood pressure, and vitamin D metabolism. 59 The toxicity mechanisms of lead are because it mimics the actions of metal ions and interacts with proteins. By substituting the essential divalent cations (Ca 2+ , Fe 2+ , and Mg 2+ ) and also by binding to the sulydryl (-SH) and amide groups (-CONH 2 ) of enzymes, lead modies their conguration and weakens their activities, resulting in malfunction of the host protein.…”
Section: Lead: Mechanism Of Its Toxicity and Carcinogenicitymentioning
confidence: 99%