Acute (toxic) epidermal necrolysis

Giallorenzi, Albert F.; Goldstein, Burton H.

doi:10.1016/0030-4220(75)90371-0

Cited by 9 publications

(3 citation statements)

References 11 publications

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“…There are two types of acute epidermal necrolysis: toxic epidermal necrolysis (Lyell's syndrome) and staphylococcal mediated epidermal necrolysis (Ritter's syndrome) [3]. Staphylococcal mediated epidermal necrolysis has been characterized as an intraepidermal bullous disease of children who are usually under the age of 10 years.…”

Section: Discussionmentioning

confidence: 99%

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Esophageal stricture secondary to drug-induced toxic epidermal necrolysis

1984

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Toxic epidermal necrolysis is a cutaneous disorder with high morbidity and mortality. Esophageal stricture has rarely been reported following recovery from this abnormality. A case is presented demonstrating the occurrence of an esophageal stricture following successful therapy. New methods of treatment are changing the mortality and morbidity such that esophageal stricture will be observed more frequently.

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Section: Discussionmentioning

confidence: 99%

“…A characteristic pathological appearance with a subepidermal cleft is seen; in staphylococcal mediated disease this cleft is in the intra-epidermal region. Toxic epidermal necrolysis has been etiologically linked to sulfonamides, barbiturate derivatives, allopurinol, phenylbutazone and several other antibiotics [2,3].…”

Section: Discussionmentioning

confidence: 99%

Esophageal stricture secondary to drug-induced toxic epidermal necrolysis

1984

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“…TEN represents the most severe variant with the highest mortality 'rate, depending on the percentage body surface area used for differentiation between TEN and SJS. 1,2,[4][5][6][7] The overall reported mortality with EM is nearly 0%, whereas SJS has a mortality of 5% to 15% and TEN has a mortality of 25% to 30%.3,8…”

Section: Discussionmentioning

confidence: 99%