Acute toxicity and residue analysis of cartap hydrochloride pesticide: Toxicological implications on the fingerlings of fresh water fish Labeo rohita

Ch., Vivek; Veeraiah, K.; Padmavathi, P.; Rao, Huan; Bramhachari, Pallaval Veera

doi:10.1016/j.bcab.2016.06.005

Cited by 20 publications

(8 citation statements)

References 34 publications

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“…(Mosiichuk et al, 2015). Vivek et al (2016) in their study found various structural aberrations like fusion of gill lamella, epithelial hyper-plasia, lamellar degeneration etc. in Labeo rohita fingerlings exposed to pesticide.…”

Section: Estimation Of Residuesmentioning

confidence: 98%

Studies on persistent organic pollutants residue in water, sediment and fish tissues of river Sutlej, India

Kaur¹,

Singh²,

Bedi³

et al. 2019

JEB

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Section: Estimation Of Residuesmentioning

confidence: 98%

Studies on persistent organic pollutants residue in water, sediment and fish tissues of river Sutlej, India

Kaur¹,

Singh²,

Bedi³

et al. 2019

JEB

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“…The exposure to environmental pollutants has been stated to cause oxidative stress and decrease the production of antioxidative agents. Cartap has been reported to cause oxidative stress in several aquatic and terrestrial organisms [ 15 , 16 ]. The establishment of oxidative stress leads to alteration in the ratio of P/A molecules in the cells.…”

Section: Discussionmentioning

confidence: 99%

“…This can result in the development of oxidative stress and cause damage to the different biomolecules [ 13 , 14 ]. The toxic impact of cartap was also reported on several non-target aquatic organisms such as Anabaena variabilis [ 15 ], Labeo rohita [ 16 ], Daphnia magna and Oryzias latipes [ 8 ]. There are inadequate reports available on the effect of cartap on the levels of toxic impacts in rats.…”

Section: Introductionmentioning

confidence: 99%

Amelioration of Hepatotoxic and Neurotoxic Effect of Cartap by Aloe vera in Wistar Rats

Gupta,

Park,

Siddiqi

et al. 2023

Toxics

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Pesticide exposure can pose a serious risk to nontarget animals. Cartap is being broadly used in agricultural fields. The toxic effects of cartap on the levels of hepatotoxicity and neurotoxicity have not been properly studied in mammalian systems. Therefore, the present work focused on the effect of cartap on the liver and brain of Wistar rats and made an assessment of the ameliorating potential of A. vera. The experimental animals were divided into 4 groups, comprising six rats in each: Group 1—Control; Group 2—A. vera; Group 3—Cartap; and Group 4—A. vera + Cartap. The animals orally given cartap and A. vera were sacrificed after 24 h of the final treatment and histological and biochemical investigations were conducted in liver and brain of Wistar rats. Cartap at sublethal concentrations caused substantial decreases in CAT, SOD, and GST levels in the experimental rats. The activity levels of transaminases and phosphatases in cartap group were also found to be substantially altered. The AChE activity was recorded as decreasing in RBC membrane and brain of the cartap-treated animals. The TNF-α and IL-6 level in serum were increased expressively in the cartap challenged groups. Histological investigation of liver showed disorganized hepatic cords and severely congested central veins due to cartap. However, the A. vera extract was observed to significantly protect against the effects of cartap toxicity. The protective impact of A. vera against cartap toxicity may be due to the existence of antioxidants in it. These findings suggest that A. vera may be developed as a potential supplement to the appropriate medication in the treatment of cartap toxicity.

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“…The sections are deparaffinized by xylol, are subjected to decreasing alcohol series and stained by haematoxylin after eosin stain. Then, they are subjected to increasing alcohol series, are cleared with xylene and mounted with coverslip by entellan [31].…”

Section: Histological Stainmentioning

confidence: 99%

Development of Embryonic Chick Liver and Distribution of eNOS, iNOS, Laminin α1

Çöllü¹,

Gürcü²

2017

Celal Bayar Üniversitesi Fen Bilimleri Dergisi

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At the embryonic development, signal transduction pathways, genetic factors, involvements between nucleus and cytoplasm, environmental factors, cell-cell and cell-matrix interactions have important roles. It has been known that the cells are regulating the Extracellular Matrix (ECM) synthesis, degradation and reshaping events, also it has been known that the Nitric Oxide is an important molecule for cellular communication and have effects on ECM molecule distribution by reacting with ECM molecules. In this reason, the purpose of our study is detecting the correlation of reactive nitrogen species with a glycosylated molecule laminin α1. In this experiment, Leghorn type SPF (Specific Pathogen Free) embryonic chick eggs have been used. Embryos are collected at 5 th , 6 th and 7 th days at incubation and taken into the 10% neutral buffered formalin solution. The liver tissues that dissected from embryos are fixated at second time. After 24 hours, it has been subjected to the routine paraffin embedding method and embedded to paraffin. From the 5µm sections, immunohistochemistry for eNOS, iNOS and Laminin α1 distribution, and for general histologic evaluation, Haematoxylene-Eosin stains has been applied. eNOS and iNOS immunoreactivity has been observed at peripheral zone of developing liver tissue that epithelialmesenchymal transition takes place. It has been determined that immunoreactivity was minimal in 5 th day, increasing with the days progressed and have highest at 7 th day. Also, eNOS staining has been more powerful than iNOS staining. Laminin immunoreactivity has been similar at all developmental stages, but relatively, has been showed lesser staining. Particularly, the presence at the zones of cell differentiation has been noteworthy.

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Acute toxicity and residue analysis of cartap hydrochloride pesticide: Toxicological implications on the fingerlings of fresh water fish Labeo rohita

Cited by 20 publications

References 34 publications

Studies on persistent organic pollutants residue in water, sediment and fish tissues of river Sutlej, India

Studies on persistent organic pollutants residue in water, sediment and fish tissues of river Sutlej, India

Amelioration of Hepatotoxic and Neurotoxic Effect of Cartap by Aloe vera in Wistar Rats

Development of Embryonic Chick Liver and Distribution of eNOS, iNOS, Laminin α1

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