Acute toxicity of cadmium to freshwater fishes and its relationship with body size and respiratory strategy

Ferro, Juan Pablo; Ferrari, Lucrecia; Eissa, Bettina Lorena

doi:10.1016/j.cbpc.2021.109109

Cited by 17 publications

(6 citation statements)

References 28 publications

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“…If fish are exposed to Cd pollution for a long time, their different tissues will absorb and accumulate Cd, thus affecting the structure and function of the gills, liver, and gonad. Furthermore, Cd affects their physiological metabolism and reproductive and immune systems and eventually leads to metabolic disorders, physical disorders, or even death [ 16 , 17 , 18 ]. Recently, studies have shown that Cd can induce various epigenetic changes, thus, changes occur in the chemical modification of DNA, histones, and chromatin, but not the sequence of DNA nucleotides, including DNA methyltransferase, histone acetyltransferase, histone deacetylase, histone methyltransferase, and microRNA.…”

Section: Introductionmentioning

confidence: 99%

Toxic Effects of Cadmium on Fish

Liu

Chen

et al. 2022

Toxics

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Large amounts of enriched cadmium (Cd) in the environment seriously threatens the healthy and sustainable development of the aquaculture industry and greatly restricts the development of the food processing industry. Studying the distribution and toxic effects of Cd in fish, as well as the possible toxic effects of Cd on the human body, is very significant. A large number of studies have shown that the accumulation and distribution of Cd in fish are biologically specific, cause tissue differences, and seriously damage the integrity of tissue structure and function, the antioxidant defense system, the reproductive regulation system, and the immune system. The physiological, biochemical, enzyme, molecular, and gene expression levels change with different concentrations and times of Cd exposure, and these changes are closely related to the target sites of Cd action and tissues in fish. Therefore, the toxic effects of Cd on fish occur with multiple tissues, systems, and levels.

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Section: Introductionmentioning

confidence: 99%

Toxic Effects of Cadmium on Fish

Liu

Chen

et al. 2022

Toxics

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“…The induction of toxicity in an organism is a complex interplay between the extrinsic environmental factors, and the degree to which an organism is responding towards those factors. The extrinsic factors such as pH, temperature, dissolved oxygen, and certain anions govern the chemical forms of the metals, whereas, the presence of suspended particles, organic matter, nutrients, etc drives the bioavailability of various contaminants in the aquatic environment 31 . In addition, it is very well documented that the exposure duration, age, sex, size, uptake pathway are some intrinsic factors that influence the toxicity at the intra and inter specie level of a metal exposure [32][33][34] .…”

Section: Discussionmentioning

confidence: 99%

Investigating the 96h LC<Sub>50</Sub> of Mercury and Cadmium on <i>Channa punctatus</i> (Bloch): A Comparative Acute Toxicity Bioassay

Sulaiman,

Zafar,

Divya

et al. 2024

JEOH

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Acute and chronic exposure of heavy metals exerts detrimental effect at the cellular level and is a rising global concern. The pollutants once introduced in the water bodies, subsequently enters the food chain, and poses risks not only to the aquatic organisms, but to the human consumers as well. Therefore, understanding the toxicological level of these metals is vital for assessing the severity of potential risks. The study aimed to conduct a comparative analysis of the acute toxicity of mercury and cadmium on Channa punctatus through a 96-hour bioassay. It was carried out in a semi-static laboratory condition following the standard guidelines. The behavioural, and mortality response was recorded at the 24, 48, 72, and 96 h of exposure duration for both toxicants. The results demonstrated distinct differences in toxicity levels between mercury and cadmium. The 96h-LC50 value for cadmium was measured at 6.19 mg/l, while for mercury, it was significantly lower at 0.44 mg/l. It was revealed that even the trace concentration of metals can induce toxicity, if given for a prolonged period of time. Furthermore, the study observed heightened toxicity of mercury, exerting adverse effects at lower concentrations compared to cadmium within the same exposure duration.

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“…Acute exposure to sublethal Cd concentrations influences alterations in endocrine status and carbohydrate metabolism in O. niloticus [81]. Research on in vitro and in vivo studies investigating the impact of Cd toxicity on freshwater fish has observed that salmonids are more sensitive to Cd [82]. Several studies suggest that even modest levels of Cd exposure disrupt the action of sex hormones in both the male and female reproductive systems of fish.…”

Section: Reproductive Effects Of Cadmium In Freshwater Fishmentioning

confidence: 99%

“…Several experimental data indicated that Cd's negative impact on gonadal development might be due to fluctuations in steroid hormonal production and expressions of sex-related genes (Tables 1 and 2). [82] Note: NA-not applicable; NS-not specified.…”

Section: Reproductive Effects Of Cadmium In Freshwater Fishmentioning

confidence: 99%

Cadmium as an Endocrine Disruptor That Hinders the Reproductive and Developmental Pathways in Freshwater Fish: A Review

Vinanthi Rajalakshmi,

Liu,

Balamuralikrishnan

et al. 2023

Fishes

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Cadmium (Cd) is a non-essential element with sub-lethal effects even at low concentrations. The persistent nature of Cd and its tendency to bioaccumulate eventually create harmful effects on water biota, including fish. Cd affects various aspects of hormonal action in fish since it bioaccumulates in the endocrine system and hinders the synthesis, secretion, and metabolic activity of hormones, causing severe damage along the hypothalamus–pituitary–gonadal axis. Linking reproductive and developmental impairments in fish with ecologically relevant concentrations of individual metals can be challenging due to the complexity of aquatic ecosystems. This review deliberated the significant and novel trends of toxicological difficulties and approaches, including elucidating environmental sources’ bioavailability and Cd-induced toxic effects in freshwater fish. Both acute and chronic exposure to Cd can cause a range of adverse effects, such as growth inhibition, impaired reproductive capacity, endocrine disruption, and developmental abnormalities in freshwater fish, as evidenced by the present review. These investigations support the concept of Cd as a naturally available pollutant that causes irreversible damage in fish. These findings will help to understand the etiology of environmental circumstances that pose substantial dangers to fish health and are also crucial for preventing and treating exposure-related reproductive disturbances in freshwater fish due to environmental pollution.

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Acute toxicity of cadmium to freshwater fishes and its relationship with body size and respiratory strategy

Cited by 17 publications

References 28 publications

Toxic Effects of Cadmium on Fish

Toxic Effects of Cadmium on Fish

Investigating the 96h LC<Sub>50</Sub> of Mercury and Cadmium on <i>Channa punctatus</i> (Bloch): A Comparative Acute Toxicity Bioassay

Cadmium as an Endocrine Disruptor That Hinders the Reproductive and Developmental Pathways in Freshwater Fish: A Review

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