Acylated Flavonoids and Phenol Glycosides from Veronica thymoides Subsp. pseudocinerea.

Abstract

Other natural products U 0800 Acylated Flavonoids and Phenol Glycosides from Veronica thymoides Subsp. pseudocinerea. -The new compounds (I) and (II) are isolated from Veronica thymoides subsp. pseudocinerea together with seven known compounds. (I) and (II) and some of the known compounds exhibit potent radical-scavenging activity against the 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical. -(SARACOGLU*, I.; VAREL, M.; HARPUT, U. S.; NAGATSU, A.; Phytochemistry 65 (2004) 16, 2379-2385; Dep. Pharmacogn., Fac. Pharm., Hacettepe Univ., TR-06100 Ankara, Turk.; Eng.) -M. Bohle 10-227

Phenolic profiling of Veronica spp. grown in mountain, urban and sandy soil environments

“…It is ecologically diverse, ranging from aquatic to dry steppe habitats and from sea level to high alpine regions (Albach, Jensen, Özgökce, & Grayer, 2005a). The phytochemistry of the genus was previously studied in some species surveyed for their iridoid (Jensen, Albach, Ohno, & Grayer, 2005;Harput, Genc, Khan, & Saracoglu, 2011) and phenylethanoid (Taskova, Gotfredsen & Jensen, 2006;Harput et al, 2011) derivatives and flavonoid glycosides (Taskova, Kokubin, Ryan, Gamock-Jones, & Jensen, 2010;Saracoglu, Varel, Harput & Nagatsu, 2004a;Albach, Grayer, Kite, Jensen, 2005b;Taskova, Kokubun, Grayer, Ryan, & Garnock-Jones, 2008;Taskova et al, 2010;Harput et al, 2011). Iridoid derivatives were mainly found as glucosides, such as aucubin, catalpol (esterified with benzoic and cinnamic acid), mussaenoside and mussaenosidic acid esters (Saracoglu et al, 2004a).…”

“…Glycosilation of these aglycones was usually observed at 5 th or 7 th position and the acylation of the sugars was another characteristic feature of some glycosides. Actually, the acylated flavone glycosides were reported as chemosystematic markers in the genus Veronica (Saracoglu et al, 2004a).…”

Phenolic profile, antibacterial, antimutagenic and antitumour evaluation of Veronica urticifolia Jacq.

“…On the other hand, the phytochemistry of the genus has been extensively studied with many species surveyed for their iridoid (Jensen et al, 2005) and phenylethanoid derivatives 5 (Taskova et al, 2006) and flavonoid glycosides (Albach et al, 2003(Albach et al, , 2005Saracoglu et al, 2004;Taskova et al, 2008) with most of these being considered beneficial for human health.…”

5-Alkylresorcinol glucosides from the leaves of Grevillea robusta Allan Cunningham

“…A compound (1a), which was claimed to have the same structure as 1, was reported to have been isolated from Veronica thymoides subsp. pseudocinerea [4]. However, its NMR data were not identical with those of 1.…”

“…The 1-BuOH-soluble fraction was separated by means of various chromatographic procedures including column chromatography (CC) on a highly porous synthetic resin (Diaion HP-20), and then silica gel and reversed-phase (ODS) CC, droplet counter-current chromatography (DCCC), and HPLC to afford four compounds (1)(2)(3)(4). The details and yields are given under ''Experimental''.…”