ADAM28 Manipulates Proliferation, Differentiation, and Apoptosis of Human Dental Pulp Stem Cells

KLF4 Promotes the Odontoblastic Differentiation of Human Dental Pulp Cells

“…ALP expression and ALPase activity (considered as early markers of odontoblast differentiation (26,27)) were found to increase with the odontoblastic induction of hDPCs. DMP1 and DSPP (also referred as odontoblastic differentiation markers (28)(29)(30)) were up-regulated during the same procedure. The formation of mineral nodules was a suggestion for odontoblastic differentiation (31).…”

The Effect of Matrix Extracellular Phosphoglycoprotein and Its Downstream Osteogenesis-related Gene Expression on the Proliferation and Differentiation of Human Dental Pulp Cells

“…However, the factors regulating the differentiation of DPCs into odontoblasts remain unclear. Studies have indicated that growth factors and extracellular matrix factors might be key groups of molecules for modulating a variety of cellular processes after dental injury (3)(4)(5).…”

Lysyl Oxidase and the Lysyl Oxidase–like Protein Modulate Odontoblastic Differentiation of Human Dental Pulp Cells

“…During dentinogenesis, dental pulp cells proliferate and differentiate into dentin-forming odontoblasts (18)(19)(20), but molecular mechanisms for controlling odontoblastic growth and differentiation remain to be further elucidated. Previously, collagen fibrils have been proposed to function as a 3-dimensional (3D) scaffold for mineral deposition during odontoblastic differentiation (21,22).…”