Adaptation and cross-cultural validation of the Spanish version of the Thyroid-Related Quality-of-Life Patient-Reported Outcome questionnaire

Boronat, Mauro; González-Lleó, Ana M.; Rodríguez-Pérez, Carlos; Feldt‐Rasmussen, Ulla; López-Plasencia, Yaiza; Rasmussen, Åse Krogh; Alberiche-Ruano, María Pino; Alvarado-Martel, Dácil; Bonnema, Steen Joop; Marrero-Arencibia, Dunia; Grøenvold, Mogens; Bjørner, Jakob Bue; Watt, Torquil

doi:10.1016/j.endien.2018.06.005

Cited by 1 publication

(3 citation statements)

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“…In international comparison, the ThyPRO-39de was performing between average and well regarding the internal consistency. It was worse than the Romanian version, which had all scales above an alpha of 0.7 ( 19 ), performed just as well as the Spanish version, which also had two scales below 0.7 ( 8 ) and was better than the Chinese version, which had 6 scales below an alpha of 0.7 ( 7 ).…”

Section: Discussionmentioning

confidence: 77%

“…These subtle differences might explain the scale’s comparatively low alpha. Interestingly, the Spanish version of the ThyPRO-39 also suffered from the low alpha in the cosmetic complaints scale ( 8 ), but adaptations into other languages did not ( 7 , 20 ). These circumstances make it difficult to determine whether there is a problem with the scale itself or its German adaptation.…”

Section: Discussionmentioning

confidence: 99%

“…To determine patient's QoL in benign thyroid diseases, a thyroid disease-specific PRO questionnaire (ThyPRO) has been developed by Watt et al in 2010 ( 5 ). In the following years, this questionnaire has been validated in different languages ( 1 , 6 , 7 , 8 ) and a shorter version called ThyPRO-39 was developed ( 9 ). So far, the ThyPRO-39 has not been validated in the German language.…”

Section: Introductionmentioning

confidence: 99%

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Validity and reliability of the German version of the shortened thyroid-specific quality of life questionnaire (ThyPRO-39de)

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Gloy

Schantzen

et al. 2021

Endocrine Connections

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Objectives: Validation of a German version of the ThyPRO-39 questionnaire for quality of life (QoL) in patients with benign thyroid diseases. Design: Internal consistency, retest-reliability and validity were to be assessed in a test-retest study. Methods: The ThyPRO-39 was translated based on standard methodology. A sample of 98 patients with benign thyroid diseases was tested with the ThyPRO-39de and the generic EuroQol 5D-5L. 44 patients with stable symptoms after 2 weeks formed the repeated-measures sample. Cronbach’s alpha was calculated for the ThyPRO-39de composite score and for each disease specific scale. Intraclass correlations between the original and the repeated measures sample were calculated for each scale as well as Pearson correlations between various ThyPRO scales and the EuroQol. T-Tests were used to test for differences in the goiter and hyperthyroid symptom scales between relevant patient groups and other patients. Results: Internal consistency was between satisfactory and good, except for two scales (Tiredness and Cosmetic complaints/appearance). The test-retest correlation was between 0.62 and 0.8 for most scales, but below 0.5 for two scales (Tiredness and Impaired social life). There were significant correlations between the EuroQol index score and most aspects of the ThyPRO-39de. Only hyperthyroid symptoms scale was specific for the relevant patient group (Graves’ disease). Conclusion: The ThyPRO-39de may be recommended for use in clinical and research settings, especially with regards to the composite score. However, the underlying thyroid disease should always be kept in mind when interpreting the test results. A larger sample would be needed to implement further improvements.

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Section: Discussionmentioning

confidence: 77%