“…Regarding distillation, it is considered that 3% of the world’s energy is used for this separation technology , as a result of its low thermodynamic efficiency (5–20%), , representing 70% of the total annual costs; in addtion, it has large environmental footprint of carbon dioxide because the heat is generated by the burning of fossil fuels. With the goal of enhancing the thermodynamic efficiency, economy, and environmental impact of the distillation systems, diverse technologies have been presented, such as configurations with interreboilers and intercondensers, heat pump systems, − multieffect columns, − thermally coupled sequences, and recently the internally heat-integrated distillation columns HIDiC. − In particular, HIDiC configurations have shown great potential energy savings compared with other technologies, especially splitting close boiling mixtures, dividing the conventional column into its corresponding rectifying and stripping sections, and generating temperature feasible driving forces between two sections (applying pressure changes) and transferring internal heat from the rectifying section (high pressure) to stripping section (low pressure).…”