“…It can also be seen, from concepts summarized in Table 2, that the nonlinear function f (•) plays an important role related to regulation of the stimulus received by B cells, since the reaction can be defined by the activation or containment of the effect of T s cells. In some works, f (•) is described by an exponential function based on antigen consistency as in [24,25,27,31,32,34]. A fuzzy inference system is also used as in [23,26,29,30,[32][33][34][35][36][37], which usually consider the total stimulation received by B cells and its variation with a time delay of immune response.…”