There are many problems in the practical application of landscape lighting design. In order to solve these problems more specifically, based on the relevant theories of interactive genetic algorithm, radial basis function and hesitation degree are introduced into genetic algorithm. Through the analysis and processing of the data to get the optimized interactive genetic algorithm, the algorithm can analyze and optimize the landscape lighting design. Based on this model, the lighting design can be predicted and analyzed, and the prediction result is relatively good. Relevant studies show that the interactive genetic algorithm can be divided into three typical change stages according to the different results of intensity calculation, of which the first stage mainly presents the trend of gradual decline. The fluctuation phenomenon is obvious in the second paragraph. The third paragraph shows a gradual increasing trend of change. The corresponding relationship between the two fitness functions is obvious. With the increase of experts in independent variables, the corresponding fitness values show a trend of gradual decline on the whole. Through the calculation and analysis of five different indicators of landscape lighting by using interactive genetic algorithm, it can be seen that electrification has a relatively small impact on landscape lighting. The results of intelligent and environmental protection calculation are relatively high, and the corresponding range of change is relatively large, which shows that these two indicators are very important for improving the lighting design level of landscape. Finally, the model is verified by comparing data and model curves. Interactive genetic algorithm is very important to improve the lighting design of landscape, and the optimization model can be widely used in other fields.