Adaptive immunity of the tympanic membrane

Poliquin, J; Catanzaro, A.; Robb, James A.; Schiff, Maurice

doi:10.1016/s0196-0709(81)80025-7

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Normal Tympanic Membrane1

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1984

1997

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Cited by 7 publications

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“…Following injury to the tympanic membrane in guinea pigs sensitized with tympanic membrane connective tissue, antibodies against type II collagen were found in high levels. This suggests that some form of autoimmunity to collagen was responsible for the tympanosclerosis‐like lesions seen in these injured drums 90,91 . Other studies however, have shown the development of tympanosclerosis even without prior sensitization to collagen 92…”

Section: Normal Tympanic Membranementioning

confidence: 97%

Overlay Versus Underlay Tympanoplasty. Part I: Historical Review of the Literature

Rizer

1997

The Laryngoscope

140

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The history of otology is the history of the successful treatment of infections of the middle ear and the eardrum. Otologists have sought to restore hearing lost to infections of the eardrum since the 1600s. The development of instruments, techniques, and materials to treat infection is fascinating because of the serendipitous nature of the discoveries and the insight of the discoverers. This historical review describes the history of the treatment of infections of the ear and the development of modern techniques of ear surgery. Two contemporary methods of tympanic membrane repair are then described.

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Section: Normal Tympanic Membranementioning

confidence: 97%