2022
DOI: 10.1101/2022.09.14.507912
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Adaptive Optical Coherent Raman Imaging of Axons through Mouse Cranial Bone

Abstract: Coherent Raman scattering imaging has provided inherent chemical information of biomolecules without the need for any external labels. However, its working depth in deep-tissue imaging is extremely shallow because both the intrinsic scattering cross-section and image contrast are so small that even weak perturbation of the pump and Stokes beam focusing by the complex tissue causes the loss of the resolving power. Here, we propose a deep-tissue coherent Raman scattering (CRS) microscopy equipped with an advance… Show more

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