Adaptive Radiation Therapy for High Grade Brain Tumors: Impact on the Dose Distribution and Disease Outcome

Radiation therapy (RT) plays a critical role in the overall management of many central nervous system (CNS) tumors. Advances in RT treatment planning, with techniques such as intensity modulated radiation therapy, volumetric modulated arc therapy, and stereotactic radiosurgery, now allow the delivery of highly conformal dose with great precision. These techniques rely on high-resolution 3-dimensional anatomical imaging modalities such as computed tomography or magnetic resonance imaging (MRI) scans to accurately and reliably define CNS targets and normal tissue avoidance structures. The integration of cross-sectional imaging into radiation oncology has directly translated into improvements in the therapeutic window of RT, and the union between radiation oncology and imaging is only expected to grow stronger. In addition, advanced imaging modalities including diffusion, perfusion, and spectroscopic MRIs as well as positron emission tomography (PET) scans with novel tracers are being utilized to provide additional insight into tumor biology and behavior beyond anatomy. Together, these standard and advanced imaging modalities hold significant potential to improve future RT delivery and response assessment. In this review, we will discuss the current utilization of standard/advanced imaging for CNS tumors from a radiation oncology perspective as well as the implications of novel MRI and PET modalities currently under investigation.

show abstract

The Role of Standard and Advanced Imaging for the Management of Brain Malignancies From a Radiation Oncology Standpoint

Press

Zhong

Gurbani

et al. 2018

Neurosurg.

View full text Add to dashboard Cite

show abstract

scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.

Contact Info

customersupport@researchsolutions.com

10624 S. Eastern Ave., Ste. A-614

Henderson, NV 89052, USA

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

Blog Terms and Conditions API Terms Privacy Policy Contact Cookie Preferences Do Not Sell or Share My Personal Information

Made with 💙 for researchers

Part of the Research Solutions Family.

Adaptive Radiation Therapy for High Grade Brain Tumors: Impact on the Dose Distribution and Disease Outcome

Abstract: Conclusion: DBF 2.0 is a user friendly web-based tool that can aid practitioners in determination of risks of early death, distant brain failure and brain metastasis velocity after SRS alone for brain metastases.

Cited by 1 publication

References 0 publications

The Role of Standard and Advanced Imaging for the Management of Brain Malignancies From a Radiation Oncology Standpoint

The Role of Standard and Advanced Imaging for the Management of Brain Malignancies From a Radiation Oncology Standpoint

Contact Info

Product

Resources

About