In this paper, the design of a distributed adaptive controller for a class of unknown nonaffine MIMO strict-feedback multi agent systems with time delay has been performed under a directed graph. The controller design is based on dynamic surface control method. In the design process, radial basis function neural networks (RBFNNs) were employed to approximate the unknown nonlinear functions. Stability analysis was performed using the Lyapunov-Krasovskii function and it was proved that all the signals of the closed-loop system are semi-globally uniformly bounded. Finally, the simulation results also confirmed the performance of the proposed control method.