In this paper, an adaptive fuzzy PD+ controller is proposed for the attitude maneuver of rigid spacecraft. The novel controller adjusts the gains of the PD+ attitude controller online according to attitude errors and angular velocity errors during the maneuver procedure. Therefore, quick response and avoidance of actuator saturation can be achieved simultaneously. Furthermore, the adaptation mechanism is designed, based on Lyapunov theory, to guarantee the stability of the closed-loop system. To achieve good performance of the closed-loop system under the constraint of actuator saturation, controller parameter optimization is developed on the basis of a genetic algorithm. Simulation results show that the transient performance and robustness against parametric uncertainty and environmental disturbance of the adaptive fuzzy PD+ controller are better than those of a constant PD+ controller.