Vehicle handing stability under the combined acceleration steering and braking steering conditions has a great impact on the vehicle safety. Therefore, the coupled steering and driving/braking stability control is essential. Thus, a novel controller based on differential flatness and vehicle stability region is proposed. First, the reference vehicle state variables are calculated and the vehicle stability region is established based on vehicle dynamics and bifurcation analysis. Then, the flatness-based controller is designed which can ensure the vehicle handing stability by controlling the vehicle states approaching their references. Based on the driver preview model, the vehicle can keep good path tracking effect by tracking the lateral deviation. The simulation results of the double lane change tests show that the proposed control method can ensure both the vehicle handing stability and the path tracking effect. Compared to vehicle equipped with the integration of active front steering and direct yaw moment control, vehicle controlled by flatness-based controller performs better in both handing stability and path tracking.INDEX TERMS Vehicle coupled control, differential flatness, stability region, handing stability, path tracking.