Added Value of Fetal MRI in the Evaluation of Fetal Anomalies of the Corpus Callosum: A Retrospective Analysis of 78 Cases

Manevich-Mazor, Mirra; Weissmann-Brenner, Alina; Yosef, Omer Bar; Hoffmann, Chen; Mazor, Roei David; Mosheva, Mariela; Achiron, R.; Katorza, E.

doi:10.1055/a-0838-9055

Cited by 3 publications

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“…Measurement of the fetal CC can be performed by trans‐vaginal or trans‐abdominal sonography . If callosal malformation is suspected an in‐utero MRI is recommended . Malformations of the CC can be characterized by agenesis (ACC), hypoplasia and hyperplasia .…”

Section: Introductionmentioning

confidence: 99%

Neurodevelopmental outcome following prenatal diagnosis of a short corpus callosum

et al. 2019

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Objective Data regarding the neurodevelopmental outcome of fetal short corpus callosum (CC) diagnosed according to standard reference charts is scarce. The purpose of this study was to assess whether the finding is related to neurodevelopmental delay, and to examine reclassification to normal fetal CC length using CC length/EFW ratio. Method Historical prospective cohort study including pregnant women who were referred for fetal neurosonogram due to abnormal CC. Short CC was defined below the 5th percentile according to reference charts. Twenty cases were included in the study group and compared with a control group of 59 normal cases. The patients in the study group were divided into two groups according to CC length/EFW ratio. Children's neurodevelopment was assessed using the Vineland Adaptive Behavior Scale (VABS). Results VABS scores were within normal range in 90% of the cases. There was no significant statistical difference between the study group and the control group. In addition, there was no statistically significant difference between fetuses reclassified as normal callosal length according to CC length/EFW ratio in comparison to the control group. Conclusion The neurodevelopmental outcome of fetuses with diagnosed short CC did not differ from the neurodevelopment of normal fetuses in the control group.

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Section: Introductionmentioning

confidence: 99%

Neurodevelopmental outcome following prenatal diagnosis of a short corpus callosum

et al. 2019

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“…Other methods or charts have been used in the literature 32–34 . Such a definition of short CC has also been used in several recent articles 32,35–38 . Sometimes, the distinction between short CC and partial ACC or CD can be very challenging and requires a thorough analysis of the CC.…”

Section: Discussionmentioning

confidence: 99%

Abnormalities of the corpus callosum. Can prenatal imaging predict the genetic status? Correlations between imaging phenotype and genotype

Nguyen,

Heide,

Guilbaud

et al. 2023

Prenatal Diagnosis

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Objective: Recent studies have evaluated prenatal exome sequencing (pES) for abnormalities of the corpus callosum (CC). The objective of this study was to compare imaging phenotype and genotype findings.Method: This multicenter retrospective study included fetuses with abnormalities of the CC between 2018 and 2020 by ultrasound and/or MRI and for which pES was performed. Abnormalities of the CC were classified as complete (cACC) or partial (pACC) agenesis of the CC, short CC (sCC), callosal dysgenesis (CD), 746

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“…An important issue concerns a condition that has been described as possibly pathologic only in the fetus: a 'short CC'. In fact, several authors have tried over the years to amass data to support this alleged condition to be considered as an abnormal entity and associated with a similarly abnormal neurodevelopmental outcome [14][15][16] . However, despite these attempts, it should be clearly emphasized that a short CC is a non-entity in the whole panorama of pediatric neuroradiology classifications and descriptions.…”

Section: The So-called 'Short Cc'mentioning

confidence: 99%

Fetal corpus callosal anomalies: from disease of classification to classification of disease

Salomon,

Paladini

2024

Ultrasound in Obstet & Gyne

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Added Value of Fetal MRI in the Evaluation of Fetal Anomalies of the Corpus Callosum: A Retrospective Analysis of 78 Cases

Cited by 3 publications

References 0 publications

Neurodevelopmental outcome following prenatal diagnosis of a short corpus callosum

Neurodevelopmental outcome following prenatal diagnosis of a short corpus callosum

Abnormalities of the corpus callosum. Can prenatal imaging predict the genetic status? Correlations between imaging phenotype and genotype

Fetal corpus callosal anomalies: from disease of classification to classification of disease

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