Addition polymerization of functionalized norbornenes as a powerful tool for assembling molecular moieties of new polymers with versatile properties

Бермешев, М. В.; Chapala, P. P.

doi:10.1016/j.progpolymsci.2018.06.003

Cited by 126 publications

(66 citation statements)

References 260 publications

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“…Strained hydrocarbons like norbornane and its non-saturated derivatives are commonly used in the production of rubber, epoxides, medicinal compounds and perfumes [ 1 , 2 ]. Notably, thermotechnical characteristics of strained hydrocarbons, which have extra internal energy due to deformation of valence bond angles, made them attractive for high-performance combustion applications [ 3 ].…”

Section: Introductionmentioning

confidence: 99%

Genotoxic effect of 2,2’-bis(bicyclo[2.2.1] heptane) on bacterial cells

et al. 2020

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The toxic effect of strained hydrocarbon 2,2'—bis (bicyclo[2.2.1]heptane) (BBH) was studied using whole-cell bacterial lux-biosensors based on Escherichia coli cells in which luciferase genes are transcriptionally fused with stress-inducible promoters. It was shown that BBH has the genotoxic effect causing bacterial SOS response however no alkylating effect has been revealed. In addition to DNA damage, there is an oxidative effect causing the response of OxyR/S and SoxR/S regulons. The most sensitive to BBH lux-biosensor was E . coli pSoxS-lux which reacts to the appearance of superoxide anion radicals in the cell. It is assumed that the oxidation of BBH leads to the generation of reactive oxygen species, which provide the main contribution to the genotoxicity of this substance.

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Section: Introductionmentioning

confidence: 99%

Genotoxic effect of 2,2’-bis(bicyclo[2.2.1] heptane) on bacterial cells

et al. 2020

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“…[15,16] There are af ew examples of Group 10 metalbased catalysts in the polymerization of alkenyl norbornenes. [17] In contrast to some early transitionm etal catalysts, [18] there is ac lear preference for the insertion of the endocyclic double bond when using Ni or Pd complexes, [19] af eature of relevance in our case towardp reservation of the terminal alkene group for further functionalization. Commercial 5-vinyl-2-norbornene (mixture of isomers endo/ exo = 79:21) was employedi nt he synthesis of 1a,w hereas 5-(but-1-en-4-yl)-2-norbornene (endo/exo = 80:20), prepared by the Diels-Alder reactiono fc yclopentadienea nd 1,5-hexadiene, [20] wasu sed in the preparation of 1b.I nb oth cases, the polymers were obtaineda sw hite solids with moderatey ields and molecular weights in the range 35-45 10 3 Da and polydispersity index values of about 2.…”

Section: Resultsmentioning

confidence: 73%

Trispyrazolylborate Ligands Supported on Vinyl Addition Polynorbornenes and Their Copper Derivatives as Recyclable Catalysts

Torre

Pérez-Ortega

Beltrán

et al. 2018

Chemistry A European J

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Polynorbornenes prepared by vinyl addition polymerization and bearing pendant alkenyl groups serve as skeletons to support trispyrazolylborate ligands (Tp ) built at those alkenyl sites. Reaction with CuI in acetonitrile led to VA-PNB-Tp Cu(NCMe) (VA-PBN=vinyl addition polynorbornene) with a 0.8-1.4 mmol incorporation of Cu per gram of polymer. The presence of tetracoordinated copper(I) ions was been assessed by FTIR studies on the corresponding VA-PNB-Tp Cu(CO) adducts, in agreement with those on discrete Tp Cu(CO). The new materials were employed as heterogeneous catalysts in several carbene- and nitrene-transfer reactions, showing a behavior similar to that of the homogeneous counterparts but also being recycled several times maintaining a high degree of activity and selectivity. This is the first example of supported Tp ligands onto polymeric supports with catalytic applications.

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“…Mitomycin C, N, N '-dimethyl-4,4' -dipyridyl dichloride (paraquat), methyl methanesulfonate obtained from Sigma Chemical Co. All test solutions were prepared immediately before use. The investigated compound 2,2 ' -bis (bicyclo[2.2.1]heptane was synthesized by the Diels-alder reaction from 5-vinyl-2-norbornene and Dicyclopentadiene according to [16] with the subsequent stage of exhaustive hydrogenation of the cycloadduct in methanol on a Pd/C catalyst (1%) with hydrogen (25°C, 20 ATM, 24 h) [1,5].…”

Section: Chemicalmentioning

confidence: 99%

Toxic effect of 2,2’-bis(bicyclo[2.2.1] heptane) on bacterial cells

Kessenikh¹,

Gnuchikh²,

Bazhenov³

et al. 2020

Preprint

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Here we present the study of the genotoxic effect of a 2,2’-bis(bicyclo[2.2.1]heptane) (BBH), which is promising as a fuel component for liquid rocket engines. The use of Escherichia coli lux-biosensors showed that in addition to DNA damage causing SOS-response, there is also an oxidative effect on cells. The greatest toxicity is determined by the mechanism of formation of superoxide anion radical and is detected by the lux biosensor E. coli pSoxS-lux, in which the genes of bacterial luciferases are transcriptionally crosslinked with the promoter of the soxS gene. It is assumed that the oxidation of BBH leads to the formation of reactive oxygen species, which should give the main contribution to the toxicity of this substance.

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Addition polymerization of functionalized norbornenes as a powerful tool for assembling molecular moieties of new polymers with versatile properties

Cited by 126 publications

References 260 publications

Genotoxic effect of 2,2’-bis(bicyclo[2.2.1] heptane) on bacterial cells

Genotoxic effect of 2,2’-bis(bicyclo[2.2.1] heptane) on bacterial cells

Trispyrazolylborate Ligands Supported on Vinyl Addition Polynorbornenes and Their Copper Derivatives as Recyclable Catalysts

Toxic effect of 2,2’-bis(bicyclo[2.2.1] heptane) on bacterial cells

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