Addition reactions of 1,1,1-trifluoro-4-trimethylstannylbut-3-yn-2-one and 1,1,1-trifluorobut-3-yn-2-one to some tetrahydropyridines. Synthesis of trifluoroacylated polysubstituted tetrahydroazocines

Abstract

A reaction of tetrahydropyridines, obtained by the Diels-Alder reaction from α,β unsat urated N,N dimethylhydrazones and methyl acrylate, with acetylenes activated with the trifluoroacetyl group has been studied and found to lead to polysubstituted trifluoroacylated tetrahydroazocines. No cyclobutene intermediates have been detected.