Addition reactions of benzo[b]thiophen. Part 4. Reactions of some acetoxy- and hydroxy-benzo[b]thiophens with benzene or toluene

Antioxidants Derived from Vitamin E: An Overview

“…Malmström and coworkers [129] decided to synthesise and study the anti oxidant capacity of a series of compound constituted by 2,3- Fig. However, for the known [131,132] sulfur derivative 123b the authors developed an efficient alternative protocol based on homolytic substitution at sulfur (Fig. Organoselenium and organotellurium analogues of -T. dihydrobenzo[b]furan-5-ol and its 1-thio, 1-seleno and 1telluro analogues (123a-d) (Fig.…”

“…126-129, Fig. On the other hand, Koufaki and co-workers encouraged the synthesis of new hybrid compounds combining the pharmacophoric redox moieties of vitamin E and key features responsible for other protective effects, like antiarrhythmic properties of the class I antiarrhythmics procainamide and lidocaine (130)(131)(132) [142], or with another antioxidant agent like lipoic acid (133)(134)(135)(136)(137)(138) [143,144]. BDEs were calculated for each and the rate reaction constant with DPPH radical.…”

“…(34)) [146]. New hybrid compounds combining the redox moieties of vitamin E and antiarrhythmic substructure (130)(131)(132), another antioxidant substructure like lipoic acid (133)(134)(135)(136)(137)(138) and catechol (139)(140)(141)(142) type of activation is observed after brain injury or infection, as well as during the development of neuropathies like Alzheimer's disease, stroke or demyelinating diseases such as multiple sclerosis. (33).…”