Additional Cover

Abstract

The cover image is based on the Original Article Tetrahedral framework nucleic acids promote diabetic wound healing via the Wnt signalling pathway by Zejing Wang et al., https://doi.org/10.1111/cpr.13316.

Tetrahedral DNA‐Based Functional MicroRNA‐21 Delivery System: Application to Corneal Epithelial Wound Healing

“…[33,34] These findings may explain why even naked tFNAs itself could enhance proliferation in many pathological conditions. [35][36][37] Given that efficient unloading of miRNAs from tFNAs is a crucial step to ensure the downstream biological functions, we demonstrated that the expression of miR-21 in HCECs significantly increased after T-21 treatment compared to control groups. This mainly attributes to the existence of RNase H, an endonuclease widely presents in mammalian cells which degrades the RNA strands of heterozygous RNA/DNA molecules while keeps single-stranded or double-stranded RNA molecules intact.…”

“…[ 33,34 ] These findings may explain why even naked tFNAs itself could enhance proliferation in many pathological conditions. [ 35–37 ]…”

Enhanced Electrochemical Characterization of the Immune Checkpoint Protein PD‐L1 using Aptamer‐Functionalized Magnetic Metal‐Organic Frameworks

“…[35][36][37] The 3.5% agarose gel electrophoresis (Figure 5C) also demonstrated that NTH consists of four ssDNA molecules. [38][39][40] By dynamic light scattering (DSL), the diameter of the NTH was measured uniformly as 13.54 nm (Figure 5D). In Figure 5E and Figure S8, Supporting Information, we illustrate that NTH exhibits a better support effect on the electrode surface than single-stranded aptamers by comparing their current values when detecting the target.…”