Additional Evidence of Stable EMF-Induced Changes in Water Revealed by Fungal Spore Germination

Rai, S.; Mishra, Gaurav; Singh, Suruchi; Samarketu,

doi:10.3109/15368379409030723

Cited by 27 publications

(4 citation statements)

References 5 publications

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“…In recent medical advances, microwaves are used in hyperthermia ablation for treatment of renal cancer (Castle et al, 2011), hepatocellular carcinoma (Liu et al, 2013), intrahepatic primary cholangiocarcinoma (Yu et al, 2011), hepatic colorectal metastases (Jones et al, 2011), metastatic liver cancer (Hompes et al, 2010), benign thyroid nodules (Yue et al, 2013), dysfunctional uterine bleeding (Bain et al, 2002), and lung cancer (Vogl et al, 2011). Microwaves can induce different biological effects as a function of field strength, frequency, wave form, and duration of exposure (Rai et al, 1994a(Rai et al, , 1994b. These effects are mainly attributed to microwave heating (Banik et al, 2003).…”

Section: Introductionmentioning

confidence: 99%

Chitosan-Carboxymethyl-5-Fluorouracil-Folate Conjugate Particles: Microwave Modulated Uptake by Skin and Melanoma Cells

Nawaz

Wong

2018

Journal of Investigative Dermatology

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5-Fluorouracil delivery profiles in the form of chitosan-folate submicron particles through skin and melanoma cells in vitro were examined using microwaves as the penetration enhancer. The in vivo pharmacokinetic profile of 5-fluorouracil was also determined. Chitosan-carboxymethyl-5-fluorouracil-folate conjugate was synthesized and processed into submicron particles by spray-drying technique. The size, zeta potential, morphology, drug content, and drug release, as well as skin permeation and retention, pharmacokinetics, in vitro SKMEL-28 melanoma cell line cytotoxicity, and intracellular trafficking profiles of drug/particles, were examined as a function of skin/melanoma cell treatment by microwaves at 2,450 MHz for 5 + 5 minutes. The level of skin drug/particle retention in vitro and in vivo increased in skin treated by microwaves. This was facilitated by the drug conjugating to chitosan and microwaves fluidizing both the protein and lipid domains of epidermis and dermis. The uptake of chitosan-folate particles by melanoma cells was mediated via lipid raft route. It was promoted by microwaves, which fluidized the lipid and protein regimes of the cell membrane, and this increased drug cytotoxicity. In vivo pharmacokinetic study indicated skin treatment by microwave-enhanced drug retention but not permeation. The combination of microwaves and submicron particles synergized skin drug retention and intracellular drug delivery.

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Section: Introductionmentioning

confidence: 99%

Chitosan-Carboxymethyl-5-Fluorouracil-Folate Conjugate Particles: Microwave Modulated Uptake by Skin and Melanoma Cells

Nawaz

Wong

2018

Journal of Investigative Dermatology

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“…In this study, the general homeostatic balance of the body of experimental rats was maintained by magnetized water which was given to them to drink ad libitum. Since there is evidence that water exposed to electromagnetic (EM) fields undergoes structural changes, and that the water ''remembers'' the field strength for an extended period of time, [10][11][12][13]16] it seems to be responsible for changing the osmolarity of tissue fluids, thereby affecting the homeostatic balance of the body. In exposed water, the angle between the two hydrogen atoms no longer remains fixed near a right angle, but becomes variable, rendering the molecule flexible.…”

Section: Discussionmentioning

confidence: 99%

“…[1][2][3][4][5][6][7][8][9][10][11][12][13][14] Still, today, there is no consensus of opinion on the effect mechanism of direct exposure to these radiations. Recently, biological effects induced by electromagnetized water have been reported, [10][11][12][13] demonstrating that EMF radiation may affect the spontaneously changing structural chemistry of biological water which, in turn, may cause bioeffects. [14] This change in structural chemistry of water is dependent upon the field strength and exposure time.…”

Section: Introductionmentioning

confidence: 99%

Magnetically Restructured Water Induces Changes in Rat Brain

Singh¹,

Singh²

2002

Electromagnetic Biology and Medicine

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Fifty-hertz power line-treated magnetically restructured water induced changes in rat brain was studied. Triple-distilled water samples were exposed to 36.2 RMS and (51.2 peak) mT power line magnetic fields for 48 hr. This magnetized water sample was given to adult male rats of Charles -Foster strain for drinking ad libitum for a period of 30 days, at the end of which the rats were anaesthetized with ether and then fixed by perfusion with 10% neutral formalin. The brains were dissected out and further fixed in the same fixative. The corresponding control rats provided with unmagnetized tripledistilled water were similarly treated. On gross examination, no anomaly was observed in the treated group. On histological examination, marked spongiform changes leading to neuronal degeneration were observed in cerebral and hippocampal cortices. The study adds a further link in demonstrating that power line exposure induced stable changes in water structures and affect biomechanisms of tissue fluids.

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“…In particular, nonthermal bioeffects have been studied on fungal spore germination after continuous-flux of waves (cw) or modulated microwave irradiation (Rai et al, 1994a(Rai et al, , 1994b. Other experiments with microwave radiation have demonstrated an electrical effect on Mimosa pudica action potential (Spanoudaki et al, 1999), an increased growth of Saccharomyces cerevisiae and Spirulina sp.…”

Section: Introductionmentioning

confidence: 98%

Nonthermal Microwave Radiations Affect the Hypersensitive Response of Tobacco to Tobacco Mosaic Virus

Betti

Trebbi

Lazzarato

et al. 2004

The Journal of Alternative and Complementary Medicine

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Additional Evidence of Stable EMF-Induced Changes in Water Revealed by Fungal Spore Germination

Cited by 27 publications

References 5 publications

Chitosan-Carboxymethyl-5-Fluorouracil-Folate Conjugate Particles: Microwave Modulated Uptake by Skin and Melanoma Cells

Chitosan-Carboxymethyl-5-Fluorouracil-Folate Conjugate Particles: Microwave Modulated Uptake by Skin and Melanoma Cells

Magnetically Restructured Water Induces Changes in Rat Brain

Nonthermal Microwave Radiations Affect the Hypersensitive Response of Tobacco to Tobacco Mosaic Virus

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