Additive antioxidant capacity of vitamin C and tocopherols in combination

Im, Sungbin; Nam, Tae Gyu; Lee, Sang Gil; Kim, Young Jun; Chun, Ock K.; Kim, Dae‐Ok

doi:10.1007/s10068-014-0094-4

Cited by 19 publications

(9 citation statements)

References 31 publications

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“…Antioxidants may render their effects via several different mechanisms including scavenging free radicals, chelating metal ions, and quenching singlet oxygen (Brewer, ). To arrive at a better antioxidant effect, a combination of different antioxidants with varied antioxidant mechanisms may be used in oils because it may provide a synergistic effect (Hraš et al, ; Im et al, ; Yin, Becker, Andersen, & Skibsted, ). In this study, four types of antioxidants including tocopherol, AP, PA, and a selected polyphenol were used to form mixtures of antioxidants.…”

Section: Discussionmentioning

confidence: 99%

“…Their antioxidant mechanisms including scavenging of free radicals (such as phenolic compounds including tocopherol, butylated hydroxytoluene (BHT), butylated hydroxyanisole (BHA), tert ‐butylhydroquinone (TBHQ), propyl gallate (PG), and various natural polyphenol extracts), chelating metal ions (such as phytic acid (PA), ethylenediaminetetraacetic acid (EDTA), and citric acid), and quenching singlet oxygen (such as ascorbic acid and ascorbyl palmitate (AP)) (Choe & Min, ). To provide a better antioxidant effect, combination of various antioxidants functioning via different antioxidant mechanisms is commonly used in oil products because of complementary and synergistic effects (Hraš, Hadolin, Knez, & Bauman, ; Im et al, ).…”

Section: Introductionmentioning

confidence: 99%

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Improving oxidative stability of flaxseed oil with a mixture of antioxidants

Yan

Wang

et al. 2019

J Food Process Preserv

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The optimum combination of antioxidants used for stabilization of flaxseed oil and extension of its shelf life was examined. To achieve this goal, based on different antioxidant mechanisms, a combination of four types of antioxidants including tocopherol, ascorbyl palmitate (AP), phytic acid (PA), and a source of polyphenol (antioxidant of bamboo leaves (AOB), rosemary extract (RE), tea polyphenols extract (TP), and tea polyphenol palmitate (TPP)) were added to flaxseed oil. The effects were monitored using peroxide value (POV), thiobarbituric acid‐reactive substances (TBARS), free radicals, and Rancimat induction time (RIT) of flaxseed oil during accelerated storage. Flaxseed oil containing 80 mg/kg tocopherol, 40 mg/kg AP, 40 mg/kg PA, and 240 mg/kg TPP was found to be more stable to oxidation than other samples and had 3.22‐fold longer shelf life than that of the control flaxseed oil. Practical applications Due to its high concentration of alpha‐linolenic acid, flaxseed oil is prone to oxidation. To improve the oxidative stability of flaxseed oil and prolonging its shelf life, the optimum formulation and ratio of mixtures of antioxidants with different antioxidant mechanisms were studied. Our results indicated that the flaxseed oil containing 80 mg/kg tocopherol, 40 mg/kg AP, 40 mg/kg PA, and 240 mg/kg TPP was very stable to oxidation. And the shelf life of the flaxseed oil containing this optimum mixture of antioxidants was 3.22‐fold longer than that of the control flaxseed oil. Therefore, adding the optimum mixture of antioxidants will help to produce the flaxseed oil products with better oxidative stability for commercial development.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Improving oxidative stability of flaxseed oil with a mixture of antioxidants

Yan

Wang

et al. 2019

J Food Process Preserv

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“…The tocopherol profile of hemp by-products is dominated by γ-tocopherol (Table 4), which is the tocopherol with the strongest antioxidant activity, but α-tocopherol is regarded as the most vital form (42,60,61). The α-tocopherol content of hemp by-products exceed dietary requirements for physiological function of growing small ruminants (10-20 mg/kg DM) and cattle (15-60 mg/kg) (33,62), but below values (270-287 mg/kg) required to extend meat shelf life (63,64).…”

Section: Phytochemical Composition Of Hemp By-productsmentioning

confidence: 99%

Bioavailability and Bioefficacy of Hemp By-Products in Ruminant Meat Production and Preservation: A Review

et al. 2020

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Plant by-products obtained from agro-industrial processes require valorisation to demonstrate their potential for enhancing animal health, meat production, and shelf life extension. One example is the fast-growing hemp industry, which produces seeds, leaves, seed oil, and cake. Studies on the nutritional value of hempseed cake have shown it can be a valuable source of protein in ruminant diets. However, there is limited documentation on the bioavailability and bioefficacy of hemp phytochemicals for improving ruminant health, production, and extending meat shelf life. The current review provides an overview of existing information on nutrient and phytochemical composition of hemp by-products, their bioavailability, and bioefficacy, and explores current limitations and prospects regarding their valorisation.

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“…Vitamin D3 is sensitive to air, heat, humidity, and light and accordingly ascorbic acid and DL-alfa tocopherol are introduced as antioxidant agent to improve stability of Vitamin D3. Vitamin C and Vitamin E acted synergically in combination [ 16 , 17 ]. The two vitamins were added in 1:1 weight ratio.…”

Section: Resultsmentioning

confidence: 99%

Development and Characterization of an Orodispersible Film for Vitamin D3 Supplementation

et al. 2020

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Vitamin D plays a crucial and very well-known role in regulation of calcium homeostasis and bone metabolism and mineralization. However, a huge and more recent body of evidence supports the positive influence of vitamin D on the regulation of immune response, ranging from protection against respiratory tract infections to prevention and management of asthma. Nevertheless, vitamin D deficiency is a very common condition and there is an increasing need for suitable products for proper supplementation, allowing good compliance also in specific populations. Orally disintegrating tablets (ODT) were first developed to overcome the difficulty experienced by pediatric and geriatric patients of swallowing traditional oral dosage forms and, recently, orodispersible films (ODF) are gaining popularity as novel dosage form for assuming active pharmaceutical ingredients, vitamins, and ingredients for food supplements. This study describes a 2000 IU Vitamin D3 ODF for daily intake, consisting of hydrophilic polymers and suitable excipients, manufactured by film-casting process. Elongation-at-break (E%), Young’s modulus (Y), and tensile strength (TS) were investigated using a dynamometer. Chemical stability was evaluated assaying the vitamin D3 in the films stored at different environmental conditions. In addition, in vitro disintegration and dissolution studies were performed. Correlation existed between the mechanical properties of the film and the residual water, acting as plasticizer. The stability study showed that vitamin D3 assay was ≥90% also after 3 months at 40 °C. The film disintegrated in less than 1 min and the vitamin D3 released was ≥75% after 15 min. An ODF with suitable properties can be manufactured and used as innovative dosage form for vitamin D3 food supplements.

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Additive antioxidant capacity of vitamin C and tocopherols in combination

Cited by 19 publications

References 31 publications

Improving oxidative stability of flaxseed oil with a mixture of antioxidants

Improving oxidative stability of flaxseed oil with a mixture of antioxidants

Bioavailability and Bioefficacy of Hemp By-Products in Ruminant Meat Production and Preservation: A Review

Development and Characterization of an Orodispersible Film for Vitamin D3 Supplementation

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