Additive effect of continuous adductor canal block and liposomal bupivacaine periarticular injection in total knee arthroplasty

Green, Evan; Frane, Nicholas; Ganz, Maximillian; Stockton, Robert; Stapleton, Erik; Mallen, Jonathan R.

doi:10.1007/s00590-019-02452-0

Cited by 5 publications

(2 citation statements)

References 27 publications

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“…On the subject of postoperative analgesia, both group A and B maintained low resting and active VAS scores from 4 to 48 hours postoperatively, endorsing the effectiveness of ACB in reducing acute postoperative pain after TKA [ 21 ]. It is universally appreciated that ACB is an ideal option for postoperative analgesia in TKA as it delivers a wider range of sensory blockade after TKA and exerts its analgesic effect without compromising quadriceps muscle strength [ 22 , 23 ].…”

Section: Discussionmentioning

confidence: 99%

Application of Preoperative Adductor Canal Block Coupled with General Anaesthesia in Elderly Patients Undergoing Total Knee Arthroplasty

Huang¹,

Zhang²,

Gao³

et al. 2022

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Objective. To investigate the clinical application of preoperative adductor canal block combined with general anaesthesia in elderly patients with total knee arthroplasty. Methods. Seventy-four patients scheduled for elective TKA in Shaanxi Nuclear Industry Hospital No. 215 were selected and were assigned into group A (continuous ACB prior to the induction of anaesthesia) and group B (continuous ACB after extraction of the tracheal catheter post-operatively) according to the random number table method. Pre and postoperative plasma adrenaline and noradrenaline levels were measured; mean arterial pressure (MAP) and heart rate (HR) were recorded at the admission and the surgical skin incision; intraoperative sufentanil dosage, number of analgesic pump presses at 48 h postoperatively; postoperative adverse effects and length of stay were recorded; resting and active VAS pain scores were assessed at 4, 8, 12, 24, and 48 h postoperatively. Results. Group B experienced a substantial increase in MAP and HR at the time of surgical skin incision, while group A registered a smaller change and a stable haemodynamic profile ( P < 0.05 ). The plasma adrenaline and norepinephrine concentrations in group B were elevated compared to the preoperative period, differentially with group A. Group A received less intraoperative sufentanil than Group B ( P < 0.05 ). Conclusion. Collectively, postoperative resting VAS scores and active VAS scores remained lower in TKA patients who were subjected to preoperative and postoperative ACB, while preoperative ACB in conjunction with general anaesthesia decreased intraoperative sufentanil dosage, contained the surgical stress response, and maintained a stable intraoperative haemodynamic state, in what is probably a preferable option for elderly patients undergoing TKA. This study has served as a reference for postoperative patients to reduce their medication and for clinicians in the treatment going forward.

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Section: Discussionmentioning

confidence: 99%

Application of Preoperative Adductor Canal Block Coupled with General Anaesthesia in Elderly Patients Undergoing Total Knee Arthroplasty

Huang¹,

Zhang²,

Gao³

et al. 2022

Disease Markers

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“…8,16) Alternatively, additional peripheral nerve block could also be considered as an analgesic supplement to overwhelm the pain after TKA. [17][18][19][20] Our second finding was the coincidence of higher pain intensity and blood loss in the No-NSAIDs group than in the control group, even if the blood transfusion rate was not different. The cTnT of No-NSAIDs group was rising during the first 48 hours after TKA and reached a statistically significant difference from the control group at 48 hours.…”

Section: Discussionmentioning

confidence: 80%

Perioperative Outcomes of Patients Who Were Not Candidates for Additional Nonsteroidal Anti-inflammatory Drugs in a Multimodal Pain Control Regimen for Total Knee Arthroplasty

et al. 2021

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Adductor canal block with or without added magnesium sulfate following total knee arthroplasty: a multi-arm randomized controlled trial

Zoratto

Phelan

Hopman

et al. 2021

Can J Anesth/J Can Anesth

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Additive effect of continuous adductor canal block and liposomal bupivacaine periarticular injection in total knee arthroplasty

Cited by 5 publications

References 27 publications

Application of Preoperative Adductor Canal Block Coupled with General Anaesthesia in Elderly Patients Undergoing Total Knee Arthroplasty

Application of Preoperative Adductor Canal Block Coupled with General Anaesthesia in Elderly Patients Undergoing Total Knee Arthroplasty

Perioperative Outcomes of Patients Who Were Not Candidates for Additional Nonsteroidal Anti-inflammatory Drugs in a Multimodal Pain Control Regimen for Total Knee Arthroplasty

Adductor canal block with or without added magnesium sulfate following total knee arthroplasty: a multi-arm randomized controlled trial

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