This article lays the foundations for an emerging research stream introducing a new framework: transformative luxury research (TLR). The framework conceptualizes the relationship between the luxury ecosystem and people's well-being, which is affected by the interaction between luxury production and consumption entities as well as macroenvironment elements. The TLR framework lies at the intersection of luxury research, macromarketing literature, and transformative consumer research. The framework focuses on the well-being of individuals and communities involved in the luxury field. TLR provides a holistic view of how interactions between the luxury consumption sphere, including different profiles of consumers, and the entities of the luxury production sphere (e.g., employees, suppliers, organizations, and communities), are shaped by macro-level luxury stakeholders. Among them are institutions, public policymakers, academics, and technology firms. How do they all affect the individual and collective well-being at the economic, cognitive, emotional, and social levels? This framework helps scholars embrace a transformative luxury research mindset to advance the literature examining the impact luxury has on people's well-being.