“…Specifically addressing emerging infections in pregnancy is important because of the potential differential impact of infections among pregnant women, the possible effects on the fetus, and the unique prophylaxis and treatment strategies necessary for efficacy and acceptability among pregnant women. 75 Attention must be paid to the successes and failures of the response to the Ebola and Zika outbreaks as physicians strive to provide excellent care for pregnant women who are affected by or at risk for emerging infectious diseases. Best practices What is current practice?…”
Understanding the pathophysiology, management, and prevention of emerging infectious diseases among pregnant women is imperative to achieve a successful response from the medical community. Ebola and Zika viruses represent infections with profound public health implications. In particular, Ebola virus is associated with high case fatality and pregnancy and neonatal loss rates, while Zika virus has been associated with multiple congenital anomalies; these features present critical clinical dilemmas for management of pregnant and reproductive aged women. The objective of this article is to summarize key background information and best practices for management of Ebola and Zika virus in pregnancy.
“…Specifically addressing emerging infections in pregnancy is important because of the potential differential impact of infections among pregnant women, the possible effects on the fetus, and the unique prophylaxis and treatment strategies necessary for efficacy and acceptability among pregnant women. 75 Attention must be paid to the successes and failures of the response to the Ebola and Zika outbreaks as physicians strive to provide excellent care for pregnant women who are affected by or at risk for emerging infectious diseases. Best practices What is current practice?…”
Understanding the pathophysiology, management, and prevention of emerging infectious diseases among pregnant women is imperative to achieve a successful response from the medical community. Ebola and Zika viruses represent infections with profound public health implications. In particular, Ebola virus is associated with high case fatality and pregnancy and neonatal loss rates, while Zika virus has been associated with multiple congenital anomalies; these features present critical clinical dilemmas for management of pregnant and reproductive aged women. The objective of this article is to summarize key background information and best practices for management of Ebola and Zika virus in pregnancy.
“…Monkeypox is one of the emerging infections of which the prevalence is increasing noticeably 5 . For instance, 75 141 monkeypox cases, including 31 (0.4%) deaths, were confirmed during the 2022 outbreak among 109 countries 6 .…”
Section: Epidemiology and Etiologymentioning
confidence: 99%
“…Literature offers limited data concerning the effects of monkeypox on pregnancy. However, its presentation does not vary among pregnant or non‐pregnant patients 5 . The usual symptoms include fever, rash (vesicles, crust), new genital lesions, or sore throat.…”
Section: Clinical Manifestations and Complicationsmentioning
The present study aimed to review monkeypox infection during pregnancy: its epidemiology and etiology, transmission, clinical manifestations and complications, diagnosis, management, antenatal testing and delivery, prevention, awareness, and recommendations. Monkeypox can spread via vertical transmission. The usual clinical symptoms include fever, rash (vesicles, crust), new genital lesions, or sore throat. It is only recommended to use cidofovir in pregnant patients when they are severely infected with monkeypox. All woman who are at high risk of exposure for monkeypox need to be vaccinated with the smallpox vaccine regardless of their pregnancy status. Monitoring includes regular non‐stress test monitoring in addition to ultrasound performed at various stages of pregnancy. High index of suspicion, informed physicians, reporting of cases, and support of research are all needed for the management of monkeypox infection during pregnancy.
“…(For a comprehensive review of additional prenatal infections, see other key references cited below. 2,3 )…”
mentioning
confidence: 99%
“…In this review, we highlight the clinical and neuroscientific lessons learned from these pathogens and how these lessons can be used to approach novel or emerging infections. (For a comprehensive review of additional prenatal infections, see other key references cited below 2,3 …”
ABBREVIATIONS BBB Blood brain barrier CRS Congenital rubella syndrome CZS Congenital Zika syndrome ZIKV Zika virus Prenatal infections have long been recognized as important, preventable causes of developmental disabilities. The list of pathogens that are recognized to have deleterious effects on fetal brain development continues to grow, most recently with the association between Zika virus (ZIKV) and microcephaly. To answer clinical questions in real time about the impact of a novel infection on developmental disabilities, an historical framework is key. The lessons learned from three historically important pathogens: rubella, cytomegalovirus, and ZIKV, and how these lessons are useful to approach emerging congenital infections are discussed in this review. Congenital infections are preventable causes of developmental disabilities and several public health approaches may be used to prevent prenatal infection. When they cannot be prevented, the sequelae of prenatal infection may be treatable.
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