Adefovir Dipivoxil, Tenofovir Disoproxil Fumarate or Lamivudine; Which is Suitable Monotherapy Medication in the Patients with Chronic Hepatitis B Virus Infection? One Year Experience

Abstract

Introduction: The hepatitis B virus infection is responsible for more than one million deaths all over the world. This study design is to compare the efficacy of Lamivudine (LAM), Adefovir Dipivoxil (ADV) or Tenofovir Disoproxil Fumarate (TDF) monotherapy in chronically infected hepatitis B patients. Methods:We design a prospective cohort study and select patients who were under treatment with TDF (300mg/day), ADV (10mg/day) and LAM (100mg/day).