Adenocarcinoma in a Benign Cystic Teratoma of the Ovary: Report of a Case with a Long Survival Period

Ueda, Gaiko; Fujita, Masami; Ogawa, Hiroyasu; Sawada, Masumi; Inoue, Masakí; Takahashi, Osamu

doi:10.1006/gyno.1993.1044

Cited by 64 publications

(52 citation statements)

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“…Patients with stage I squamous cell carcinoma have a 77% 5-year survival rate, but the prognosis is poor in those with advancedstage disease (68). Adenocarcinoma is the second most frequent type arising in dermoid cysts, and the prognosis is similar to that of squamous cell carcinoma (69). Rare cases of Paget disease have been described (70,71).…”

Section: Carcinoma Groupmentioning

confidence: 98%

Recent Advances in the Pathology and Classification of Ovarian Germ Cell Tumors

Roth

Talerman²

2006

International Journal of Gynecological Pathology

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In recent years, our knowledge of ovarian germ cell tumors has increased, and their classification has evolved. The introduction of cisplatin-based chemotherapy and the discovery of tumor markers, including alpha-fetoprotein and human chorionic gonadotropin, have dramatically changed the clinical outlook for most of these patients. In this review, recent advances in the classification and pathology of ovarian germ cell tumors are discussed. Where appropriate, comparisons are made with testicular germ cell tumors. The last section of the article discusses the pathogenesis of germ cell tumors. This review will emphasize the articles written in the last 10 years and those that have significantly advanced our knowledge of germ cell tumors in past decades.

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Section: Carcinoma Groupmentioning

confidence: 98%

Recent Advances in the Pathology and Classification of Ovarian Germ Cell Tumors

Roth

Talerman²

2006

International Journal of Gynecological Pathology

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“…Malin değişimlerin %93 ünü karsinomlar,%7 sini sarkomlar oluşturur. Bunlar içinde skuamöz hücreli karsinom en yaygın olanıdır ve dermoid tümörlerden kaynaklanan tümörlerin yaklaşık %70 ini kapsar (6). Bu kistler ço-ğunlukla skuamöz epitel ile örtülü olduğundan olguların çoğunu skuamöz hücreli karsinomun oluşturması mantıklı gözükmektedir.…”

Section: Discussionunclassified

Malign Transformation In Mature Cystic Teratoma Of Ovary Of A Breast Cancer Patient: Squamous Cell Carcinoma

Gürbüz¹,

Kurt²,

Canda³

et al. 2013

Tepecik Dergisi

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ÖZETOverin matür kistik teratomunun malin transformasyonu oldukça nadir olup %1-2 sıklıkta görülmektedir. Yaklaşık 1 yıl önce meme kanseri nedeni ile tedavi gören 30 yaşındaki kadın hastanın sağ overinde skuamöz karsinom odağı içeren 9 cm lik bir matür kistik teratom saptadık.Anahtar Sözcükler: Malin transformasyon,Matür kistik teratom, Skuamöz hücreli karsinom. SUMMARYMalign transformation of mature cystic teratoma of ovary is extremely seldom(1-2%).A 9-cm mature cystic teratoma of ovary was diagnosed in a 30 years old woman who was treated for breast cancer about one year ago.Histopathologic examination revealed that teratoma has a small focus of squamous cell carcinoma .

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“…Chemotherapeutic regimens for germ cell tumor, regimens for histological types of malignant transformation and the use of texane have been reported [18] , but none of these regimens are established treatments. For adenocarcinoma, regimens using 5-fl uorouracil, CDDP, paclitaxel, mitomycin, cyclophosphamide and CPT-11 have occasionally been reported [19][20][21][22] .…”

Section: Discussionmentioning

confidence: 99%

Use of the Collagen Gel Droplet Embedded Drug Sensitivity Test to Determine Drug Sensitivity against Ovarian Mature Cystic Teratoma with Malignant Transformation to Adenocarcinoma: A Case Report

et al. 2007

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Background: The collagen gel droplet embedded drug sensitivity test (CD-DST) is a new anticancer drug sensitivity test that only requires a small number of cells. We report the use of this test in the choice of adjuvant chemotherapy for treatment of a rare case of ovarian cancer involving malignant transformation of ovarian mature cystic teratoma. Case Report: The patient was a 70-year-old female with an ovarian tumor, pleural effusion, carcinomatous ascites and a chest wall tumor. The histopathological diagnosis was adenocarcinoma, mature cystic teratoma with malignant transformation, stage IV. Paclitaxel/carboplatin therapy was selected as adjuvant chemotherapy based on CD-DST results. Upon completion of 6 courses, no increases in carcinomatous ascites or recurrent lesions were evident, and the chest wall tumor had disappeared completely. Conclusion: The CD-DST may be particularly useful for selecting preoperative chemotherapeutic drugs for patients with ovarian cancer in which the histological type of the primary tumor is unknown.

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Adenocarcinoma in a Benign Cystic Teratoma of the Ovary: Report of a Case with a Long Survival Period

Cited by 64 publications

References 0 publications

Recent Advances in the Pathology and Classification of Ovarian Germ Cell Tumors

Recent Advances in the Pathology and Classification of Ovarian Germ Cell Tumors

Malign Transformation In Mature Cystic Teratoma Of Ovary Of A Breast Cancer Patient: Squamous Cell Carcinoma

Use of the Collagen Gel Droplet Embedded Drug Sensitivity Test to Determine Drug Sensitivity against Ovarian Mature Cystic Teratoma with Malignant Transformation to Adenocarcinoma: A Case Report

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