Adenocarcinoma of the Appendix

Abstract

Objective: To report the experience of our department on adenocarcinoma of the appendix through a series of six (6) cases. Materials and Methods: This is a retrospective study carried out from January 2010 to June 2015 collating all cases of adenocarcinoma of the appendix diagnosed at the department of visceral surgery B in Hassan II University Hospital in Fez. Results: Six cases of adenocarcinoma of the appendix were recorded during the determined period of study. The mean age was 54.67 ± 16.99 years with the extreme ages ranging from 28 to 78 years. There was a female predominance with a sex ratio of 2. All patients had no specific medical history. The revealing symptoms were the following: appendicitis syndrome (1 case), bowel obstruction (1 case), psoas abscess (1 case) and fortuitous discovery during laparotomy for another problem (3 cases). The following histological types found were: colloid adenocarcinoma (3 cases), mucinous adenocarcinoma (2 case), mucinous cystadenocarcinoma associated with a moderately differentiated adenocarcinoma of the appendix (1 case). The surgical procedure consisted of a right hemicolectomy in 3 patients. Appendectomy followed by a right hemicolectomy and drainage of psoas abscess was performed in two patients. Palliative ileocecal resection and Bouilly-Volkmann ileocolostomy was performed in one patent who had carcinosis. All patients received adjuvant chemotherapy. The following occurred during follow-up: carcinosis (2 patients), a locoregional recurrence (2 patients). Two patients never returned for follow-up. Conclusion: Tumor of the appendix is a rare and exceptional pathology. These tumors are generally discovered fortuitously or during histology of appendectomy specimens. The treatment is usually surgical.

Clinical Presentation and Prognostic Factors of Primary Appendix Malignancies: A Retrospective Evaluation

“…Adenokarsinomlar, bu vakaların yaklaşık üçte ikisini temsil eder ve müsinöz, müsinöz olmayan (veya kolonik tip) ve taşlı yüzük hücreli histolojik alt tiplerine ayrılabilir (1). Ortalama tanı yaşı, yaşamın beşinci dekadıdır, erkeklerde daha yüksek insidansa sahip olabilen kolloid adenokarsinomlar hariç tüm alt tipler eşit erkek/kadın oranı ile temsil edilir (12). Bizim çalışmamızda medyan yaş 58 (25-76, min-max) yıldı ve tüm hastaların %65,5'ini kadın hastalar oluşturmaktaydı.…”