Adenocarcinoma of the esophagus in an 8-year-old boy

Esophageal adenocarcinoma: a review and perspectives on the mechanism of carcinogenesis and chemoprevention

“…More and more evidence, however, has shown alone (38). There is synergism between duodenal contents and that CLE is an acquired disease, although the possibility of gastric contents in inducing CLE, although either of them congenital origin cannot be excluded in some rare cases (16).…”

Esophageal adenocarcinoma and squamous cell carcinoma in children and adolescents: Report of 3 cases and comprehensive literature review

“…The median age at presentation was 15 years (range, 8–21 years). The youngest patients to present with an AC and SCC were each 8 years old [10, 20]. All other patients (40/42 patients [95.2%]) presented in the second decade of life.…”

“…gastrectomy,transverse colon interposition 12 NED EA repair in infancy, tumor distal to site of EArepair Kumar, 1992 19/M18/M17/M middlemiddledistal poorwellpoor lungbrainno palliative presternal gastric pull-uppalliative radiotherapypartial esophagectomy esophagogastrostomy,adjuvant chemotherapy2 4212 DODDODNED Hassall, 1993 17/M15/M19/M distaldistaldistal not notednot notednot noted noliverlymph node total esophagectomy, gastric pull-upnot notednot noted 36not notednot noted NEDDODDOD patient with spastic quadriplegiapatient with cerebral palsypatient with cerebral palsy McGill, 1993 16/F GEJ poor lymph node esophagogastrectomy andgastroesophagostomy, adjuvantchemotherapy3 30 NED Gangopadhyay, 1997 8/M middle not noted not noted therapy refused 6 DOD Sasaki, 1999 11/F GEJ not noted lymph node endoscopic polypectomy, distalesophagectomy, proximal gastrectomy a...…”

Pathology of Pediatric Gastrointestinal and Liver Disease

“…Adenocarcinoma in children with BE is extremely rare, but it has been reported in those as young as 8 years old (Gangopadhyay et al 1997 ).…”

“…8.12 ) (Polit 1990 ). Twenty-four cases of esophageal carcinoma occurring in children ranging from 8 to 20 years old have been reported to date (Issaivanan et al 2012 ;Al Hilou et al 1984 ;Schettini et al 1998 ;Gangopadhyay et al 1997 ;Zotter et al 2001 ). The esophagus can also be involved by respiratory papillomatosis (Batra et al 2001 ).…”