Adenocarcinoma of the rectovaginal septum probably arising from endometriosis

Lash, S.R.; Rubenstone, Albert I.

doi:10.1016/0002-9378(59)90178-4

Cited by 23 publications

(4 citation statements)

References 10 publications

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“…On the other hand, obesity also increases the risk for developing cancer from endometriosis. Three of the 8 women with rectovaginal tumors arising from endometriosis were obese (Table 1) [23, 24]. Our patient did not use unopposed estrogens, but her BMI was above normal.…”

Section: Discussionmentioning

confidence: 86%

Endometrioid adenocarcinoma of the rectovaginal septum with invasion of the rectum: a case report and review of literature

et al. 2019

World J Surg Onc

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BackgroundMalignant transformation of endometriosis in the rectovaginal septum is rare and usually misdiagnosed as a colorectal or gynecological tumor. We report a rare case of primary endometrioid adenocarcinoma of the rectovaginal septum with invasion of the rectum.Case presentationA 57-year-old overweight woman presented with vaginal bleeding and self-reported left lower abdominal pain during the previous 2 weeks. Preoperative imaging showed a large pelvic mass with invasion of the rectum, suggestive of a gynecologic malignancy. Multiple endoscopic biopsies and immunohistochemical analyses of specimens was performed. The patient received joint gynecological-surgical laparotomy, and there were no intra- or postoperative complications. The histopathological diagnosis was rectovaginal endometrioid adenocarcinoma with rectum infiltration. The patient received adjuvant chemotherapy and achieved good treatment response, with no early complications. At 12 months after surgery, there was no evidence of recurrence.ConclusionsA high index of clinical suspicion is required for the diagnosis of endometrioid adenocarcinoma in the rectovaginal septum. Surgery combined with additional chemotherapy or radiotherapy seems to be a standard treatment, and hormonal therapy is optional. The efficacies of other therapies, including targeted medication and immunotherapy, are unknown.

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Section: Discussionmentioning

confidence: 86%

Endometrioid adenocarcinoma of the rectovaginal septum with invasion of the rectum: a case report and review of literature

et al. 2019

World J Surg Onc

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“…Primary adenocarcinoma of the rectovaginal septum is an extremely rare clinical entity. In the literature, only seven documented cases meeting Sampson's criteria have been reported (4–9) (Table 1). Our case fulfilled all these criteria.…”

Section: Discussionmentioning

confidence: 99%

“…Carcinoma developing in endometriosis outside the ovary is decidedly rare. Primary adenocarcinomas located in the rectovaginal septum have already been reported; however, to our knowledge only seven cases have been described so far (4–9) . We report a case of a primary adenocarcinoma of the rectovaginal septum arising from endometriosis.…”

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confidence: 80%

Primary adenocarcinoma arising from endometriosis of the rectovaginal septum: a case report

Yazbeck

Poncelet

Chosidow

et al. 2005

Int J Gynecol Cancer

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Adenocarcinomas developing in endometriotic lesions have been reported, most commonly in the ovary. The rectovaginal septum is a rare location of this neoplastic transformation. We report a case of primary adenocarcinoma arising from endometriosis of the rectovaginal septum in a 25-year-old woman presenting with lower abdominal pain and dyspareunia. Diagnostic and treatment modalities were discussed. Immunohistochemical studies of different keratin subtypes and CA125 expression of the tumor cells are of interest for the diagnosis. Preoperative radiation therapy promotes clinical symptoms relief, tumor volume reduction, and better radical surgical approach.

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“…Primary vaginal carcinoma is extremely rare, according for reportedly 1–3 % of all gynecological malignancies [ 6 , 7 ]. There are few reports of carcinoma arising in the neovagina.…”

Section: Case Presentationmentioning

confidence: 99%

Mucinous adenocarcinoma emerging in sigmoid colon neovagina 40 years after its creation: a case report

et al. 2015

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BackgroundWe reported our experience of adenocarcinoma of sigmoid colon neovagina.Case presentationA 67-year-old female with a history of neovagina construction for Rokitansky syndrome complained of vaginal bleeding. She had a mucinous adenocarcinoma at the anterior aspect of the neovagina. Her original surgery, using sigmoid colon to construct the artificial vagina, was 40 years agoConclusionsThis patient’s case may contribute to our understanding of carcinogenesis in the colon.

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Adenocarcinoma of the rectovaginal septum probably arising from endometriosis

Cited by 23 publications

References 10 publications

Endometrioid adenocarcinoma of the rectovaginal septum with invasion of the rectum: a case report and review of literature

Endometrioid adenocarcinoma of the rectovaginal septum with invasion of the rectum: a case report and review of literature

Primary adenocarcinoma arising from endometriosis of the rectovaginal septum: a case report

Mucinous adenocarcinoma emerging in sigmoid colon neovagina 40 years after its creation: a case report

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