Adénocarcinome polymorphe de bas grade : une localisation labiale

Campana, Fabrice; Fakhry, Nicolas; Grande, Jean Del; Ordioni, Ugo

doi:10.1051/mbcb/2014025

Cited by 2 publications

(2 citation statements)

References 7 publications

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“…As for postoperative radiotherapy, there is no established benefit, although this approach has been practiced by many authors, except for certain limited cases such as lymph node metastases, incomplete resections, and inoperable patients. [18]. Uemaetomari et al deemed postoperative radiotherapy necessary, but a large retrospective study conducted by Castle et al showed that 97% of patients did not experience recurrence approximately a decade after their surgery.…”

Section: Discussionmentioning

confidence: 99%

A Case Report and Literature Review on Polymorphous Low-Grade Adenocarcinoma of the Parotid Gland

et al. 2024

IJFMR

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Polymorphous low-grade adenocarcinoma (PLGA) poses challenges in diagnosis, both clinically and histologically, owing to its subtle clinical manifestations and diverse microscopic patterns. The aggressive nature observed in minor salivary glands, in contrast to major glands, seems to be histologically linked to the prevalence of the papillary pattern. However, the biological behavior of PLGA in major salivary glands remains uncertain, as evidenced by cases exhibiting recurrences and metastases irrespective of the presence of a papillary pattern. We report a case of a 56-year-old patient, diagnosed with a PLGA, the computed tomography (CT) of the facial mass objectified a 2 x 1.5 cm multicystic tumoral left parotid mass.The patient underwent an excisional biopsy of the mass, followed by histological examination and immunohistochemical testing, which indicated the presence of a polymorphous low-grade adenocarcinoma. (PLGA). The treatment consisted of surgery (left parotidectomy) followed by adjuvant radiotherapy.

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Section: Discussionmentioning

confidence: 99%

A Case Report and Literature Review on Polymorphous Low-Grade Adenocarcinoma of the Parotid Gland

et al. 2024

IJFMR

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“…Il n'y a pas de bénéfice établi de la radiothérapie postopéra-toire même si ce type de thérapie a été pratiqué par de nombreux auteurs sauf pour certains cas limités incluant les métas-tases ganglionnaires, les exérèses incomplètes et les patients non opérables [20].…”

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Adénocarcinome polymorphe de bas grade du palais mou : revue et rapport de cas

Naji

Alaoui

Yahya

2016

Med Buccale Chir Buccale

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Résumé -Introduction : L'adénocarcinome polymorphe de bas grade (APBG) est une tumeur maligne rare qui se trouve presque exclusivement située dans les glandes salivaires accessoires. Il survient fréquemment chez les patients entre 30 et 70 ans, avec un ratio femme-homme de 2/1. Il est généralement situé dans le palais dur ou mou. Observation : Il s'agissait d'une patiente de 38 ans, consultant suite à l'apparition d'une tuméfaction bleutée au niveau du palais mou droit, évoluant depuis un an, indolore et recouverte d'une muqueuse d'aspect normal. Le diagnostic évoqué était un adénome pléomorphe mais l'examen histologique après exérèse chirurgicale révélait un APBG. Une reprise des marges d'exérèse était nécessaire associée à une plastie. Discussion : Le diagnostic de l'APBG est basé principalement sur les éléments cliniques et radiologiques. L'anatomopathologie permet la confirmation et la classification de la lésion. Le traitement reste essentiellement chirurgical. Le pronostic est bon malgré un taux de récidive de l'ordre de 17 % à 24 %. Bien que rares, les métastases dans les ganglions lymphatiques régionaux peuvent se produire dans 9 % des cas. Conclusion : L'APBG est une tumeur non agressive dont le pronostic dépend de plusieurs facteurs dont le délai de consultation, d'où l'importance d'un dépistage précoce.Abstract -Polymorphous low-grade adenocarcinoma of the soft palate: review and case report. Introduction: Polymorphous low-grade adenocarcinoma (PLGA) is a rare malignant tumor that is found almost exclusively in the minor salivary glands. It frequently occurs in patients between 30 and 70 years old, with a female to male ratio of 2/1. It is usually located in the hard or soft palate. Observation: A 38-year-old female patient presented with a bluish swelling in the right side of the soft palate which had evolved for a year, which was painless and covered with a mucosa of normal appearance. The first diagnosis suggested was pleomorphic adenoma, but the histologic exam following the surgical biopsy revealed a PLGA. Surgical revision of the safety margins was necessary together with mucosal plasty. Discussion: The diagnosis of PLGA is based mainly on clinical and radiological aspects, but a histologic exam is absolutely necessary to confirm it, and for classification of the lesion. Treatment is mainly surgical. The prognosis is good, although the recurrence rate is 17% to 24%. Although seldom, metastases in regional lymph nodes may occur in 9% of cases. Conclusion: PLGA is a non-aggressive tumor whose prognosis depends on several factors including the consultation period. This highlights the importance of early detection.

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Adénocarcinome polymorphe de bas grade : une localisation labiale

Cited by 2 publications

References 7 publications

A Case Report and Literature Review on Polymorphous Low-Grade Adenocarcinoma of the Parotid Gland

A Case Report and Literature Review on Polymorphous Low-Grade Adenocarcinoma of the Parotid Gland

Adénocarcinome polymorphe de bas grade du palais mou : revue et rapport de cas

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