Adenoid-cystic carcinoma (cylindroma) of the pyriform sinus in pediatric age

Campora, E. De; Croce, A; Bicciolo, G.; Radici, Marco

doi:10.1016/0165-5876(87)90036-x

Cited by 9 publications

(8 citation statements)

References 11 publications

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“…The majority are located in the oral cavity and histologically are MEC. Other sites reported include the nasopharynx [28] , larynx (subglottic) [29] , and piriform fossa [30] .…”

Section: Malignantmentioning

confidence: 98%

Salivary Gland Neoplasms in Children and Adolescents

Bradley

Eisele

2016

Salivary Gland Neoplasms

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Salivary gland neoplasms (SGNs) in children are uncommon. Epithelial SGNs (ESGNs) comprise the majority (95%), with the remaining being mesenchymal SGNs (MeSGNs). Pleomorphic adenoma is the most frequently encountered benign neoplasm, mucoepidermoid carcinoma is the most frequent malignant ESGN, and rhabdomyosarcoma is the most frequent malignant MeSGN. ESGN presents in the second decade, whereas MeSGN presents in the first and second decades. Swelling without pain or neurological signs is the main presentation of both benign and malignant neoplasms. Making an accurate preoperative histological diagnosis is important, so a needle biopsy or a perioperative frozen section is useful when there is doubt about the disease status of the patient; the excised tumour margin is also important. Surgical excision should aim to achieve clear margin excision in benign and malignant ESGNs, minimising the need for adjuvant radiotherapy and maximising the long-term likelihood of patient cure. Benign ESGNs are uncommon, and excision is curative, whereas malignant ESGN and MeSGN should be managed by a multidisciplinary paediatric oncology team.

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“…The majority are located in the oral cavity and histologically are MEC. Other sites reported include the nasopharynx [28] , larynx (subglottic) [29] , and piriform fossa [30] .…”

Section: Malignantmentioning

confidence: 98%

Salivary Gland Neoplasms in Children and Adolescents

Bradley

Eisele

2016

Salivary Gland Neoplasms

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“…In another series of 57 patients aged 20 years or younger 27 , the histologic types of the 38 carcinomas were MEC 19, acinic cell carcinoma 7, ACC 6, secretory carcinoma (mammary analogue) 4 and myoepithelial carcinoma 2. Moreover, it is possible to find in the literature some case reports of unusual locations of ACC in childhood: an 8-year-old girl with ACC of the external auditory canal 28 , a 15-year-old boy with ACC of the larynx 29 and a 12-year-boy with ACC of the pyriform sinus 30 .…”

Section: Epidemiologymentioning

confidence: 99%

Adenoid cystic carcinoma. An indolent but aggressive tumour. Part A: from aetiopathogenesis to diagnosis

Cantù

2021

Acta Otorhinolaryngol Ital

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Adenoid cystic carcinoma (ACC) is a relatively rare tumour of the minor and major salivary glands. It is uncommon in the parotid gland while it is much more frequent in the submandibular gland and in minor salivary and mucinous glands (oral cavity, oropharynx, and paranasal sinuses). ACC may also arise in secretory glands located in other tissues, such as in the tracheobronchial tree, oesophagus, breast, lungs, prostate, uterine cervix, lachrymal and Bartholin's glands, and skin. The natural history of ACC is characterised by an indolent growth rate, a relatively low probability of regional lymph node metastases and a high likelihood of haematogenous dissemination. ACC has been traditionally subdivided into three histological groups (cribriform, tubular, and solid) based on solid components of the tumour. Some studies have shown that tumours with a solid growth component have a rapid fatal course, compared to tumours without a solid growth component, but other studies have failed to correlate growth patterns with clinical course. The purpose of this review is to analyse the very large number of studies (sometimes contradictory) on ACC. In this first part, the aetiology, epidemiology, histopathology, clinical behaviour and diagnostic workup are examined. KEY WORDS: adenoid cystic carcinoma, salivary gland tumours, head and neck cancer, prognostic factors RIASSUNTO Il carcinoma adenoide cistico (ACC) è un tumore relativamente raro ad origine dalle ghiandole salivari minori e maggiori. È poco frequente nella parotide mentre lo è molto di più nella ghiandola sottomandibolare, nelle ghiandole salivari minori e in quelle mucinose del cavo orale, orofaringe e seni paranasali. Esso può anche insorgere nelle ghiandole secretrici localizzate in altri tessuti come l'albero tracheo-bronchiale, l'esofago, la mammella, il polmone, la prostata, la cervice uterina, la cute, le ghiandole lacrimali e quelle del Bartolini. La sua storia naturale è caratterizzata da una lenta crescita, da rare metastasi linfonodali e da frequenti metastasi a distanza. Dal punto di vista istologico esso è stato tradizionalmente suddiviso in tre forme (cribriforme, tubulare e solido). Alcuni studi hanno dimostrato che i tumori con una prevalente componente solida hanno una prognosi peggiore rispetto a quelli con prevalente componente cribriforme o tubulare ma altri studi hanno contestato questa affermazione. Il proposito di questa review è quello di analizzare il grande numero di pubblicazioni (talvolta contraddittorie) sul carcinoma adenoide cistico. In questa prima parte saranno discusse l 'eziologia, l'epidemiologia, l'istopatologia, la presentazione clinica e l'iter diagnostico.

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“…In the two cases of malignant tumours in the pharynx, oropharynx [23] and hypopharynx [21], it was possible to perform local excision, and primary closure, with preservation of local functions. Both cases were treated surgically only.…”

Section: Surgery Of the Minor Salivary Glandsmentioning

confidence: 99%

“…A 12-year-old with adenoid cystic carcinoma of the larynx was treated by total laryngectomy and post-operative radiotherapy same as for an adult patient [22]. The use of radiation therapy should be considered in selected and individual cases only and not as a routine as advocated in similar adult cases [21,39].…”

Section: Surgery Of the Minor Salivary Glandsmentioning

confidence: 99%

“…There have been more benign cases reported than malignant cases, with an odds ratio of up to 10: 1 benign to malignant [18][19][20] . In spite of this, malignant salivary gland tumours have been reported in children in other sites of the head and neck: maxilla (acinic cell carcinoma), lip and tongue (mucoepidermoid carcinoma), vallecular (acinic cell carcinoma), piriform fossa (adenoid cystic carcinoma), and larynx (adenoid cystic carcinoma), all malignant [21][22][23] .…”

Section: Introductionmentioning

confidence: 99%

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Paediatric Salivary Gland Epithelial Neoplasms

Bradley

McClelland

Mehta

2007

ORL

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Salivary gland epithelial neoplasms in children are rare. Clinicians of all disciplines need to have a high level of suspicion when a non-inflammatory single mass lesion presents in the parotid or submandibular glands. There is high likelihood of malignancy when such a mass presents. Surgery is the primary treatment of choice in the majority of cases, with the addition of adjuvant radiotherapy ± chemotherapy when the diagnosis is a high-grade tumour and/or when the malignancy presents as a large mass or is associated with local tissue invasion. Minor salivary gland neoplasms also present, the oral cavity is most frequent, with pleomorphic adenoma and mucoepidermoid carcinoma being most common, other malignant neoplasms have been reported in other sites.

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Adenoid-cystic carcinoma (cylindroma) of the pyriform sinus in pediatric age

Cited by 9 publications

References 11 publications

Salivary Gland Neoplasms in Children and Adolescents

Salivary Gland Neoplasms in Children and Adolescents

Adenoid cystic carcinoma. An indolent but aggressive tumour. Part A: from aetiopathogenesis to diagnosis

Paediatric Salivary Gland Epithelial Neoplasms

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