Adenoid Cystic Carcinoma of Maxillary Sinus Misdiagnosed as Chronic Apical Periodontitis

Park, So Young; Pi, Chien Yun; Kim, Euiseong; Lee, Y.

doi:10.1016/j.joms.2017.01.023

Cited by 4 publications

(2 citation statements)

References 20 publications

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“…The tumor generally causes enlargement of the involved gland in the form of a lump or nodule in the periauricular and/or infra-auricular areas, or significant swelling of the affected side of the face sometimes can reach an extensive size if neglected [ 10 ]. Furthermore, SACC of the parotid has been reportedly associated with an odontogenic-like pain referring to the maxillary sinus and sialolithiasis [ 11 , 12 ]. Salivary adenoid cystic carcinoma of the submandibular gland can present as a slow-growing swelling in the floor of the mouth, often interfering with speech and mastication thus readily detectable or in the form of a lump affecting the submandibular area or presenting in the posterior lower border of the mandible on the affected side [ 13 ].…”

Section: Resultsmentioning

confidence: 99%

Adenoid Cystic Carcinoma of Salivary Glands: A Ten-Year Review and an Assessment of the Current Management, Surgery, Radiotherapy, and Chemotherapy

Saleh

Ukwas

2023

International Journal of Otolaryngology

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Adenoid cystic carcinoma (ACC) is a rare cancer that arises from the salivary glands and other sites in the body, such as the lung and breast. Although the tumor accounts for 10% of all salivary gland malignancies, it only accounts for 1% of head and neck malignancies. It can affect both major and minor salivary glands; here, it is called salivary gland adenoid cystic carcinoma or SACC, with a slight predilection to the latter, and commonly manifests between the 6th and 7th decades of life. The disease also shows a slight female predilection, with a reported female to male ratio of 3 : 2. Lesions of SACC are often insidious and slow-growing, and symptoms such as pain and altered sensation are frequently associated with advanced stages of the disease. Salivary adenoid cystic carcinoma is characterized by perineural invasion (PNI), a distinctive feature that potentially plays a significant role in the tumor’s relapse and recurrence, which is approximately 50%. The disease is not prevalent, and its etiopathogenesis is poorly understood, although several genetic patterns and biomarkers have been linked to its initiation and/or progression. The discovery of these mutations and biomarkers has encouraged several clinical studies to use therapeutic agents to target the specific receptors on the cancer cells to potentially prevent further proliferation of the tumor cells and metastasis of the disease. Diagnosis of SACC is often challenging and frequently requires a combination of clinical examination, imaging, and histopathology. Management of SACC is primarily surgical excision, while radiotherapy has shown to be effective in improving local control in cases with microscopic residual disease. However, treatment of recurrent or metastatic tumors by radiotherapy with or without chemotherapy has so far shown limited success. The aim of this thesis is to provide an update of literature on SACC with a particular focus on the latest management approaches and future trends.

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Section: Resultsmentioning

confidence: 99%

Adenoid Cystic Carcinoma of Salivary Glands: A Ten-Year Review and an Assessment of the Current Management, Surgery, Radiotherapy, and Chemotherapy

Saleh

Ukwas

2023

International Journal of Otolaryngology

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“…It is a well known fact that the pain arising from non-dental causes might be confused as pain arising from the tooth, which leads to misdiagnosis. Park et al ., reported an adenoid cystic carcinoma of maxillary sinus misdiagnosed as chronic apical periodontitis ( 8 ),Therefore, pain associated to salivary gland malignant tumor may be misdiagnosed as pain from odontogenic origin.…”

Section: Discussionmentioning

confidence: 99%

Case of Unrecognised of Maxillary Adenoid Cystic Carcinoma

Juras¹,

Škrinjar²,

Manojlović³

et al. 2019

Acta Stomatol Croat

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Adenoid cystic carcinoma is a less commonly diagnosed cancer that may affect the major or minor salivary glands. We present a 70 year old male patient who was admitted to the Department of Oral Medicine, School of Dental Medicine in Zagreb, Croatia due to pain in the right maxilla. In this case we report a case of the patient with unilateral pain in the maxilla & eye which lead to the diagnosis of adenoid cystic cancer without any visible oral lesions.

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