Adenoid Cystic Carcinoma of the Head and Neck

Kim, Kwang Hyun; Sung, Myung Whun; Chung, Phil‐Sang; Rhee, Chae Seo; Park, Chan Il; Kim, Woo Ho

doi:10.1001/archotol.1994.01880310027006

Cited by 171 publications

(142 citation statements)

References 21 publications

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“…Surgery of the primary tumor remains as initial treatment of choice for ACC, and frequently it is complemented by neck dissection, whose value is still under discussion in the literature [2] and this is usually followed by postoperative radiotherapy; however, there has not been established yet an effective systemic management for recurrent or metastatic ACC, and it is not known if systemic therapy impacts on the course of the disease [3]. The aim of our study is to analyze the demographic data, clinical behavior, surgical management of the primary tumor and neck management of adenoid cystic carcinoma (ACC), as well as to describe the adjuvant treatment with radiation therapy, disease free survival and survival in Mexican Mestizos.…”

Section: Introductionmentioning

confidence: 99%

Adenoid Cystic Carcinoma in a Mexican Population

Luna-Ortiz¹,

Villavicencio-Valencia²,

Rodriguez-Falconi³

et al. 2015

J. Maxillofac. Oral Surg.

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Objective To analyze the demographic data, clinical behavior, management (surgery/radiotherapy), disease-free survival (DFS) and overall survival (OS) in Mexican Mestizos with adenoid cystic carcinoma (ACC).Material and Methods A retrospective study comprising all cases with histologic diagnosis of ACC of the head and neck treated from 1986 to 2012. Results There were 101 cases (69 women and 32 men), with a mean age of 50 years; mean evolution time before diagnosis was 25 months (range 1-180 months). Most tumors involved maxillary sinus (25.8 %), followed by hard palate (15.9 %) and parotid gland (10.9 %). Surgery was the treatment in 81 cases (80.2 %), radiotherapy alone in 3 cases (3 %), chemo-radiotherapy in 4 cases (4 %) and 13 cases (12.9 %) did not receive any treatment. Postsurgery adjuvant radiotherapy was used in 58 cases (57.4 %); 6 cases (5.9 %) had adjuvant chemo-radiotherapy after surgery and 37 (36.6 %) cases did not receive any adjuvant treatment. Mean follow-up time was 52 months (range 1-288 months). Histologic patterns were cribriform (50.5 %), solid (28.7 %), and tubular (11.9 %) types. OS was 57.6 % and 42.3 % at 5 and 10 years respectively. DFS was 57.8 % at 5 years and 49.7 % at 10 years. Conclusions Initial management in most cases within this series was surgery followed by radiotherapy. There is more to learn about real benefits of molecular therapies. There were no significant differences in DFS and OS depending on site of involvement. OS did not show statistically significant differences amongst patients with positive and negative lymph nodes.

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Section: Introductionmentioning

confidence: 99%

Adenoid Cystic Carcinoma in a Mexican Population

Luna-Ortiz¹,

Villavicencio-Valencia²,

Rodriguez-Falconi³

et al. 2015

J. Maxillofac. Oral Surg.

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“…The tumor is slowly growing, less aggressive and with infrequent lymph node metastasis. Perineural invasion is a common feature of this lesion [23]. Immunohistochemistry show positive staining of the myoepthelial cells for S100, actin and calponin.…”

Section: Pathology Of Basal Squamous Cell Carcinomamentioning

confidence: 80%

Basaloid Squamous Cell Carcinoma

Brambilla¹,

Lantuéjoul²,

Nicholson³

et al. 2012

High-Yield Uropathology

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“…The present study confi rms previous reports [6,[10][11][12]] the palatal mucosal glands are more frequently involved than any other group of intraoral minor salivary glands. Kim et al [13], have also reported frequent occurrence of ACC in minor salivary glands of the nose and paranasal sinuses. Surgery was the prime treatment to Adenoid cystic carcinoma like in the others studies [1,5,6,8,12].…”

Section: Discussionmentioning

confidence: 95%

Adenoid Cystic Carcinoma of the Maxilla, CT Follow-Up: A Case Report

Caputo¹,

Filho²,

Costa³

et al. 2017

Int J Radiol Radiat Oncol

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Background: Intraoral adenoid cystic carcinoma is an uncommon pathology with a variable clinical course, it develops as a slow growing swelling characterized by wide local infi ltration. Most patients are in their fourth and sixth decades of life, and females are slightly more affected than males.Case report: An 46-years-old woman was seen at University Hospital of Cuiabá with strong pain in the upper edge of the right side region. Patient reported being subjected to tooth extraction in the area where the pain was equivalent to 4 years, and in intraoral examination revealed an increase in volume of the region of the right side palate. The patient was submitted to the radical surgery promoting the removal of the lesion in the areas of the right maxilla, maxillary sinus and fl oor of the right orbit. The diagnosis was adenoid cystic carcinoma and after one year of follow-up the patient showed no presence of recurrences.

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Adenoid Cystic Carcinoma of the Head and Neck

Cited by 171 publications

References 21 publications

Adenoid Cystic Carcinoma in a Mexican Population

Adenoid Cystic Carcinoma in a Mexican Population

Basaloid Squamous Cell Carcinoma

Adenoid Cystic Carcinoma of the Maxilla, CT Follow-Up: A Case Report

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