Adenoid Cystic Carcinoma of the Parotid Gland

Blanck, C; Eneroth, C.-M.; Jacobsson, Folke; Jakobsson, Å.

doi:10.3109/02841856709138576

Cited by 78 publications

(23 citation statements)

References 5 publications

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“…Metastatic growths were occasionally found in the liver or in bones (table X). According to similar findings by other authors (1,3,15,21) only 3 of our patients showed metastatic lesions in regional or supraregional lymph nodes which could be clearly separated from local recurrences. Distant metastasis occurred after only 5 years or more in 4 patients.…”

Section: Metastasissupporting

confidence: 66%

“…Therefore, irradiation may reduce the size of the tumour but does not destroy it completely to prevent recurrences (1,4,10,(16)(17)(18)22). Solid tumours apparently are especially radiosensitive (3). However, the sensitivity of adenoid cystic carcinoma to irradiation is controversial (9,15).…”

Section: Irradiationmentioning

confidence: 99%

“…Lymphogenous metastasis in adenoid cystic carcinomata occurs more in frequently and later than blood-bome metastasis (1,3,15,21). According to Schdrer and Zollinger (21) distant metastatic lesions are frequent (27%) and mainly affect the lung (3).…”

Section: Metastasismentioning

confidence: 99%

“…According to histological characteristics the tumour was later classified as a growth of 'intermediate malignancy ' (20) or of 'questionable malignancy' (21). However, the clinical course demonstrated that this tumour should not only justifiably but of necessity be included among the carcinomata because of its tendency to recur (3,21), to spread along nerve sheaths (3,15,17,18) and to show haematogenous metastasis (1,3,6,15,21), together with a duration of several years and pains of difficult therapeutic control. The term 'adenoid cystic carcinoma' should be used instead of 'cylindroma' to prevent the minimization of this tumour (14,23).…”

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confidence: 99%

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Adenoid Cystic Carcinoma of the Head and Neck

Chilla¹,

Schroth²,

Eysholdt³

et al. 1980

ORL

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Histological re-examination of 64 adenoid cystic carcinomata showed that 15 of them were different tumours, mainly adenocarcinomata. The remaining 49 adenoid cystic carcinomata were solid in 6 cases, cribriform in 24 cases and tubular in 14 cases. No precise classification was possible in 5 cases of adenoid cystic carcinoma. Uncontrollablefactors important for the prognosis of adenoid cystic carcinomata included the histological type and the site of the tumour: major salivary glands (28 cases), area of paranasal sinuses (11 cases) and minor salivary glands (10 cases). Adenoid cystic carcinomata of tubular type or situated in minor salivary glands had a relatively favourable prognosis related to survival rate, ‘state of health’ and tendency to recurrence. Controllablefactors exerted a favourable influence on the commonly poor prognosis of adenoid cystic carcinomata. They included an early diagnosis and, because of the tendency to recurrence, radical surgery and radiotherapy. The poor long-term prognosis of this tumour was due to a tendency to local recurrence (80% of cases) and mainly haematogenous metastasis (37% of cases). Lymphogenous metastasis was less frequent (6% of cases).

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Section: Metastasissupporting

confidence: 66%

Section: Irradiationmentioning

confidence: 99%

Section: Metastasismentioning

confidence: 99%

mentioning

confidence: 99%

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Adenoid Cystic Carcinoma of the Head and Neck

Chilla¹,

Schroth²,

Eysholdt³

et al. 1980

ORL

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“…ACC constitutes 15% of tumors of the submandibular gland, but only 2-6% of tumors of the parotid gland [11,14]. Clinical features at presentation (nasal obstruction, swelling and facial pain) are nonspecific and more than 50% of patients have had symptoms for 1-5 years before presentation [11].…”

Section: 21 Adenoid Cystic Carcinomamentioning

confidence: 99%

Perineural tumor extension along the trigeminal nerve: magnetic resonance imaging findings

Majoie

Hulsmans

Verbeeten

et al. 1997

European Journal of Radiology

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General rightsIt is not permitted to download or to forward/distribute the text or part of it without the consent of the author(s) and/or copyright holder(s), other than for strictly personal, individual use, unless the work is under an open content license (like Creative Commons). Disclaimer/Complaints regulationsIf you believe that digital publication of certain material infringes any of your rights or (privacy) interests, please let the Library know, stating your reasons. In case of a legitimate complaint, the Library will make the material inaccessible and/or remove it from the website. Please Ask the Library: http://uba.uva.nl/en/contact, or a letter to: Library of the University of Amsterdam, Secretariat, Singel 425, 1012 WP Amsterdam, The Netherlands. You will be contacted as soon as possible. AbstractObjectice: To evaluate the magnetic resonance imaging (MRI) findings of 15 patients with perineural tumor extension along the trigeminal nerve in correlation with clinical data. ,~Iethods: The clinical records and MRI studies of 15 patients with perineura.l tumor extension along the trigeminal nerve were retrospectively reviewed. Imaging studies included plain and contrast-enhanced thin section Tl-weighted spin echo (T1-WSE) MRI with and without fat-suppression. The studies were compared to determine which sequence provided greatest tumor conspicuity and best depiction of tumor extent. The conspicuity of these tumors was assessed on the available sequences by two observers by consensus. Results: The contrast-enhanced Tl-weighted spin echo fat-suppressed images (TI-WSECEFS) demonstrated greatest tumor conspicuity and best depiction of tumor extent in the extracranial head and neck and skull base region. The conventional Tl-weighted spin echo pre-and postcontrast images were, however, diagnostic of perineural tumor extension in 11 patients due to the presence of considerable tumor bulk and extension well above the skull base. In the other four patients the perineural tumor was poorly visualized on the conventional TI-WSE images and well visualized on the fat-suppressed images. The mandibular division of the trigeminal nerve (V3) was most commonly involved (n = 10), followed by the maxillary. (V2; n = 5) and ophthalmic (VI; n = 2) division. Two patients had both mandibular as well as maxillary nerve involvement. The finding of perineural tumor extension had significant impact on patient management: based on the MR imaging study, the primary tumor was considered inoperable (n = 13), the extent of surgery was expanded (n = 2) and radiation therapy (RT) ports were extended (n = 12). Conclusion: Complete trigeminal nerve imaging is recommended when evaluating (suspected) head and neck malignancies with a high risk for perineural extension. In these cases thin section axial and coronal precontrast T1-WSE MR images and postcontrast TI-WSE MR images with fat-suppression should be obtained. In the rare event that artifacts degrade the quality of the fat-suppressed images, contrast-enhanced TI-WSE sequences without fat...

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