Adenoid cystic carcinoma of the head and neck (ACCHN) incidence and survival trends.

Intraoral adenoid cystic carcinoma: is the presence of perineural invasion associated with the size of the primary tumour, local extension, surgical margins, distant metastases, and outcome?

“…18 However, in contrast to oral squmous cell carcinoma, ACC has good 5-year survival ranging from 78% to 90%, while 10 and 20-year survival rates are much worse due to negative survival impact of delayed recurrences (range 32-74%). 8,13,14,19,20 We found no statistically significant association between PNI and primary tumour size. On the contrary, van der Wall et al 1 implicated a significant relation between the size of the tumour and PNI.…”

Disparities in Postoperative Therapy for Salivary Gland Adenoid Cystic Carcinomas

“…Our series also confirmed known factors that influence overall survival in head and neck cancers including age, sex, comorbidity status, extent of resection, and tumor stage. 7,10,13,[21][22][23] Interestingly, in this analysis we found that patients with private insurance and patients living closer to their treatment facility had improved OS, perhaps due to improved access to care. In our series, with limited follow-up, the receipt of adjuvant radiation or chemotherapy was not associated with improved OS.…”

Patterns of care and survival of adjuvant radiation for major salivary adenoid cystic carcinoma

“…Conflicting data exist on gender as a prognostic indicator. One study showed that it was not prognostic at all, 24 whereas a Surveillance, Epidemiology, and End Results study showed improved overall survival among women, 25 and another analysis showed worse disease-free survival. 26 Our results showed that when stratified by margin status, the benefit of adjuvant radiation was not sustained among patients with negative margins (P 5 .053).…”