Adenomyoma of the jejunum

Adenomyoma of the small intestine in an adult: Report of a case

“…6 We found 24 case reports of this entity in the published literature. 2,4,5,[7][8][9][10][11][12][13][14][15][16][17][18][19][20][21][22][23][24] This report describes a further case of adenomyoma in the small intestine, followed by a review of the pertinent literature.…”

Adenomyoma of the small intestine

“…The glandular epithelial cells of the lesion do not express CDX-2, a marker of intestinal mucosal epithelium [26] . The smooth muscle cells surrounding the glandular elements are positive for α-smooth muscle actin and desmin ( Figure 6) [20,23] .…”

“…Immunohistochemically, the glandular element of adenomyoma of the small intestine is positive for cytokeratin (CK) 7 ( Figure 5A) and negative for CK 20 (Figure 5B) [23,26] , while normal intestinal epithelial cells around the lesion are negative for CK 7 and positive for CK 20. The glandular epithelial cells of the lesion do not express CDX-2, a marker of intestinal mucosal epithelium [26] .…”

“…Several authors reported cases with the transitional area between the epithelial component of the adenomyoma and epithelium of the overlying mucosa and considered it to be evidence that the epithelial component of the lesion originated from the epithelium of the small intestine [21,26] . In general, CK 7 is distributed in the pancreatic duct epithelium but is essentially absent in GI epithelium.…”

Adenomyoma of the Ileum Leading to Intussusception

“…Although this lesion originates from abnormal embryonic buds, which can differentiate into pancreatic or duodenal tissue, its pathogenesis has not been fully elucidated. It is generally considered to represent either myoepithelial hamartoma or a form of heterotopic pancreatic tissue [1]. …”