Adenomyosis: Diagnosis by Hysteroscopic Endomyometrial Biopsy, Correlation of Incidence and Severity with Menorrhagia

Abstract

There is a definite correlation between menorrhagia and adenomyosis both in incidence and depth of penetration.

Adenomyosis: US Features with Histologic Correlation in an in Vitro Study

“…In one series, the diagnostic rate in the same uteri varied between 31% and 62%, depending on the number of samples obtained (21). Although adenomyosis is seen in both symptomatic patients and asymptomatic patients, it appears to be more common in symptomatic patients (3,22). The variable appearance of adenomyosis at US relates to the distribution of the heterotopic endometrial tissue, the presence and degree of associated muscle hypertrophy, and the presence and size of the cysts within the heterotopic endometrial tissue.…”

Effect of menstrual cycle and hormonal treatment on ki-67 and bcl-2 expression and adenomyosis

“…The observations that the local release of levonorgestrel in the uterine cavity can cause regression of adenomyosis is further evidence that these lesions can respond to high intrauterine doses of progestins by reducing proliferation and augmenting apoptosis in a similar way to that occurring in the eutopic endometrium [6,14,15]. This is in agreement with our findings that the presence of Mirena in the uterine cavity decreases proliferation and bcl-2 expression in adenomyosis more efficiently than oral contraceptive pills, which were able effectively to reduce proliferation but not bcl-2 expression.…”

Operative Therapie der Endometriose

“…Optische Veränderungen des Endometriums (Endometriuminvaginationen, Trabekulationen, Regionen einer Neovaskularisation) weisen auf eine Adenomyosis hin. Durch Gewinnung eines histologisch zu untersuchenden Präparates wird die Diagnose gesichert [29]. Die Entnahme einer Endometriumbiopsie mit der elektrischen Schlinge des Resektoskops ist eine Mög-lichkeit.…”