Adenosine Deaminase Activity a Biomarker for Rheumatoid Arthritis: Review

Abstract

Rheumatoid arthritis (RA) is an autoimmune, chronic, inflammatory and symmetric disease. In order to avoid joint destruction and reduce requires knowledge of the vital components causing the disease; so it is essential to start early in diagnosis and suitable treatment. Although clinical symptoms and results of radiographic help to identify and measure the activity of RA disease, biochemical markers also act as indicators of early diagnosis of the disease activity. So it is therefore the diagnosis of the disease in an early stage must choose a strong relationship with the disease. One of the vital signs related to rheumatoid arthritis is adenosine deaminase (ADA). The destruction of adenosine by the adenosine pathway facilitates a series of infections such as rheumatoid arthritis. So there are many questions that come to our mind namely. Can the level of adenosine activity (ADA) be a biomarker of the distinction between RA patients and controls? Can adenosine deaminase be a biomarker indicator for diagnosing of rheumatoid arthritis at the stage early pre-radiographically? And, does adenosine deaminase activity give an indication of the disease activity? In this review article, we're going to show the studies that pointed to those questions.

Evaluate The Correlation Serum Afamin Level With Some Biochemical Parameters In The Sera Of Patients With Type 2 Diabetes Mellitus

“…Also, Pearson's correlation coefficient was used to explore the relationships between the afamin level and the variables studied. P-values of 0.05 were considered statistically significant [19].…”