Adenosine monophosphate degradation and inosinic acid accumulation in the shrimp Penaeus japonicus

Seki, Hiroko; Nakazato, Kaori; Hamada‐Sato, Naoko

doi:10.1007/s40071-017-0154-5

Cited by 12 publications

(4 citation statements)

References 35 publications

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“…More specifically, resistant mice had significantly higher levels of IMP (inosinic acid) and AMP (adenosine monophosphate) in the vmPFC immediately following social defeat compared to susceptible mice. AMP is produced during adenosine triphosphate (ATP) synthesis, while IMP is generated via ATP degradation in two metabolic pathways in which AMP is generated and then degraded to either IMP or adenosine ( Seki et al., 2017 ). Taken together, these two molecules are indicative of increased cellular activity in the vmPFC of resistant mice.…”

Section: Discussionmentioning

confidence: 99%

Metabolomics reveals distinct neurochemical profiles associated with stress resilience

Dulka

Bourdon

Clinard

et al. 2017

Neurobiology of Stress

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Acute social defeat represents a naturalistic form of conditioned fear and is an excellent model in which to investigate the biological basis of stress resilience. While there is growing interest in identifying biomarkers of stress resilience, until recently, it has not been feasible to associate levels of large numbers of neurochemicals and metabolites to stress-related phenotypes. The objective of the present study was to use an untargeted metabolomics approach to identify known and unknown neurochemicals in select brain regions that distinguish susceptible and resistant individuals in two rodent models of acute social defeat. In the first experiment, male mice were first phenotyped as resistant or susceptible. Then, mice were subjected to acute social defeat, and tissues were immediately collected from the ventromedial prefrontal cortex (vmPFC), basolateral/central amygdala (BLA/CeA), nucleus accumbens (NAc), and dorsal hippocampus (dHPC). Ultra-high performance liquid chromatography coupled with high resolution mass spectrometry (UPLC-HRMS) was used for the detection of water-soluble neurochemicals. In the second experiment, male Syrian hamsters were paired in daily agonistic encounters for 2 weeks, during which they formed stable dominant-subordinate relationships. Then, 24 h after the last dominance encounter, animals were exposed to acute social defeat stress. Immediately after social defeat, tissue was collected from the vmPFC, BLA/CeA, NAc, and dHPC for analysis using UPLC-HRMS. Although no single biomarker characterized stress-related phenotypes in both species, commonalities were found. For instance, in both model systems, animals resistant to social defeat stress also show increased concentration of molecules to protect against oxidative stress in the NAc and vmPFC. Additionally, in both mice and hamsters, unidentified spectral features were preliminarily annotated as potential targets for future experiments. Overall, these findings suggest that a metabolomics approach can identify functional groups of neurochemicals that may serve as novel targets for the diagnosis, treatment, or prevention of stress-related mental illness.

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Section: Discussionmentioning

confidence: 99%

Metabolomics reveals distinct neurochemical profiles associated with stress resilience

Dulka

Bourdon

Clinard

et al. 2017

Neurobiology of Stress

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“…A number of E. oxidotolerans T-2-2 T strains, like STR36, AMBL-20 T, SGAA-2, A011, N4-1p, CNU020, Kopri 20,246, and isolate 2, have been isolated from variety of the habitats like rhizosphere, glaciers, corals, sea mud and sediments, dead brown algae, and shrimps. These strains played a major role in enzyme production, such as exopolysaccharide and alkaline lipase production, and showed antimicrobial activity and Bgl1C (β-glucosidase), catalase, and protease activity, and were useful for industrial applications (Lee et al 2005;Chen et al 2010;Bharti et al 2013;Cai et al 2014;Chellaram et al 2015;Seki et al 2017;Yasin et al 2021).…”

Section: Discussionmentioning

confidence: 99%

Isolation and identification of a pathogenic bacterium, Exiguobacterium oxidotolerans XP-2, from the abnormal diseased mature sporophytes of a commercially cultivated brown seaweed Saccharina japonica

Chen

Zhuang

Qiu³

et al. 2021

J Appl Phycol

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Diseases of the commercially cultivated brown seaweed Saccharina japonica have been noticed since the 1960s in China. However, the usually opportunistic nature of the pathogenic bacteria of seaweeds is still a main obstacle for isolating and identifying pathogenic bacteria responsible for causing diseases of the cultivated S. japonica. In this study, a Gram-positive bacterium XP-2 was isolated from the abnormal diseased mature sporophytes of S. japonica. Pathogenicity test indicated that XP-2 could cause green-rotten disease in healthy juvenile sporophytes and significant algal ultrastructural changes were observed after S. japonica was infected by XP-2. The cells shrank, and the thylakoids of the chloroplasts became blurred after 12 h of re-infection. At 24 h slight deformation was observed in the structure of the mitochondria, chloroplasts, and nucleus. There also were many vacuoles in the infected cells. After 31 h of re-infection, mitochondrial structure and thylakoids became more indistinct. SEM and TEM observations indicated that XP-2 was rod-shaped with no flagella. Analysis of the full length 16S rRNA gene sequence and physiological and chemical characteristics indicated that XP-2 was closely related to Exiguobacterium oxidotolerans 12280 T . Based on these results, XP-2 was designated Exiguobacterium oxidotolerans XP-2. The pathogenicity of E. oxidotolerans XP-2 was identified by Koch's Postulate under laboratory conditions. These results enrich the growing list of pathogenic bacteria in commercially cultivated seaweeds and also provide a foundation for investigating the virulence mechanisms of pathogenic bacteria of commercially cultivated seaweeds in the near future.

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“…Salt waste (Bittern), a by-product of salt production, is a potential raw material for the production of magnesium hydroxide since magnesium ions were found in high quantity together with several other components such as Na + , K + , and Ca 2+ . Bittern has been used directly as a supplement beverage (nigari) [1], fish preservatives [2,3], and industrial waste coagulant [4][5][6]. Indirectly, bittern is used as raw materials such as in fertilizer manufacture [7][8][9], the raw material for production of potassium salt [10,11], and manufacture of various magnesium compounds, such as magnesium oxide (MgO) [12], magnesium sulfate [13] and magnesium hydroxide (Mg(OH) 2 ) [14] .…”

Section: Introductionmentioning

confidence: 99%

Effect of Dilution and Electrolysis Time on Recovery of Mg2+ As Mg(OH)2 from Bittern by Electrochemical Method

Amrulloh

Simanjutak

Situmeang

et al. 2019

J. Pure App. Chem. Res.

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This research was conducted to study the effect of dilution and electrolysis time on the recovery of Mg 2+ as Mg(OH) 2 from bittern by electrochemical method. The electrochemical process was carried out using 2-compartment electrochemical cell, connected by salt bridge prepared from NaCl suspended in gelatin. The experiment was carried out using nickel as cathode and carbon as an anode. The electrolysis process was carried out at a potential of 18 volts with dilution factors of 0, 2, 4, 6, and 8 times, and electrolysis time of 1, 2, 4, 6, 8, 10, and 12 hours. The results show that percent of conversion increased with dilution with the best result was obtained at 4x dilution factor and 4 hours electrolysis time with percent conversion of 85 % and purity of Mg(OH) 2 91%.

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Adenosine monophosphate degradation and inosinic acid accumulation in the shrimp Penaeus japonicus

Cited by 12 publications

References 35 publications

Metabolomics reveals distinct neurochemical profiles associated with stress resilience

Metabolomics reveals distinct neurochemical profiles associated with stress resilience

Isolation and identification of a pathogenic bacterium, Exiguobacterium oxidotolerans XP-2, from the abnormal diseased mature sporophytes of a commercially cultivated brown seaweed Saccharina japonica

Effect of Dilution and Electrolysis Time on Recovery of Mg2+ As Mg(OH)2 from Bittern by Electrochemical Method

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