“…These variable results are questionable because positive associations were essentially reported by a limited group of authors from similar institutions and because Ad36 was identified using serology in these studies. Discrepancies in detection and specificity may exist between studies using serology and those using viral culture or polymerase chain reaction detection ( 35 ). Moreover, conclusions originate from observational studies; thus, a causal relation between Ad36 infection and obesity cannot be proven.…”