2023
DOI: 10.21203/rs.3.rs-3482325/v1
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Adenovirus 36 seropositivity influences the expression of anti-adipogenic lncRNAs GAS5 and MEG3 in adipose tissue obtained from subjects with obesity

Alvaro Cerda,
Victor Manriquez,
Roberto Brito
et al.

Abstract: Background Adenovirus 36 (Ad-36) promotes adipogenesis and the development of human obesity. Induction of PPARγ by Ad-36 seems to have a central role in maintenance of adipogenic status. There is limited information about epigenetic mechanisms contributing to this process in human adipose tissue. This study evaluated the expression of lncRNAs (ADINR, GAS5 and MEG3) and miRNAs ((miR-18a and miR-140) involved in adipogenic process in visceral adipose tissue (VAT) of subjects with obesity with previous Ad-36 infe… Show more

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