Adenovirus-Associated Acute Appendicitis: An Under-Recognized Relationship?

Lynch, David T.; Lott, Lisa; Cebe, Katherine; McDonald, J. Matthew; Abplanalp, Allison; Tully, Charla C; Trujillo-Lopez, Elizabeth; Danaher, Patrick

doi:10.7205/milmed-d-16-00308

Cited by 15 publications

(10 citation statements)

References 13 publications

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“…[ 17 ] Research shows that appendicitis is associated with viral infection, and the virus has seasonal epidemics. [ 18 ] Clinically, we found that the number of pediatric with appendicitis was high in summer and autumn. This leads us to investigate whether appendicitis has a significant seasonality.…”

Section: Introductionmentioning

confidence: 94%

Association of meteorological factors with pediatric acute appendicitis in China

et al. 2018

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Acute appendicitis (AA) affects between 7% and 8% of the world population and is one of the most common general surgical emergencies. The concept of seasonal patterns in the incidence of AA remains controversial. Thus, this study aimed to investigate whether meteorological factors are related to variations in the rate of pediatric AA cases at the Children's Hospital in Chongqing, China.In total, in this retrospective survey, 3436 children younger than 18 years who had been hospitalized with AA from January 1, 2008 to December 31, 2013 were enrolled, and the meteorological factors during this period were collected.Patients with AA showed a male/female ratio of 1.81:1; the highest incidence age ranged from 6 to 12 years old (P < .0001). The highest incidences of pediatric AA occurred in summer and autumn, with a peak in September and a trough in February. Pearson correlation analysis showed that the monthly mean temperature (r = 0.357, P = .001), monthly mean relative humidity (r = −0.357, P = .001), and monthly mean sunshine duration (r = 0.235, P = −0.031) were relatively weak correlated with pediatric AA. Multiple linear regression analysis indicated that pediatric AA occurrence was positively affected by monthly mean temperature (P < .0001) and negatively affected by monthly mean humidity (P < .0001) and monthly sum of sunshine (P < .0001), while monthly mean air pressure (P = .092), monthly wind speed (P = .143) and monthly precipitation (P = .297) were marginally associated with pediatric AA.Pediatric AA is associated with climatic factors. Specifically, pediatric AA is more likely related to the following meteorological conditions of: high temperature (20 °C–30 °C), low humidity, and less sunshine.

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Section: Introductionmentioning

confidence: 94%

Association of meteorological factors with pediatric acute appendicitis in China

et al. 2018

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“…Therefore, active nursing intervention after caesarean section is of great significance. However, the traditional nursing model can no longer meet the actual needs of patients, evidence‐based nursing is a novel modern clinical nursing model, the core is ‘patient‐centred’, through the changes in the patient's condition, combined with the clinical practice experience and scientific and safety evidence‐based nursing practice basis, to meet the patient's needs for diversified nursing services, and thus achieve more satisfactory nursing results 42 …”

Section: Discussionmentioning

confidence: 99%

“…However, the traditional nursing model can no longer meet the actual needs of patients, evidence-based nursing is a novel modern clinical nursing model, the core is 'patientthrough the changes in the patient's condition, combined with the clinical practice experience and scientific and safety evidence-based nursing practice basis, to meet the patient's needs for diversified nursing services, and thus achieve more satisfactory nursing results. 42 Wound infection is one of the most common complications 43 that affects women in labour, and in severe cases can be septic and even life-threatening. 44,45 Our results showed that the incidence of wound infection and complications in the experimental group was significantly reduced after evidence-based nursing intervention, which is a significant improvement compared with the control group.…”

Section: Discussionmentioning

confidence: 99%

Impact of evidence‐based nursing on surgical site wound infection after caesarean: A meta‐analysis

Zhang,

Wu,

Zhang

et al. 2024

International Wound Journal

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We conducted this study to investigate the effect of evidence‐based care on surgical site wound infection after caesarean section. A computerised search of PubMed, Embase, Google Scholar, Cochrane Library, China National Knowledge Infrastructure and Wanfang databases for randomised controlled trials (RCTs) on the use of evidence‐based care in caesarean section delivery was applied from the database inception to November 2023. Two researchers independently screened the literature, extracted data and performed quality assessment based on inclusion and exclusion criteria. Stata 17.0 software was applied for data analysis. Twenty‐one RCTs involving 3269 caesarean sections were finally included. The analysis revealed the implementation of evidence‐based nursing interventions was effective in reducing the incidence of post‐caesarean section wound infections (OR = 0.29, 95% CI: 0.21–0.39, p < 0.001) and complications (OR = 0.29, 95% CI: 0.23–0.38, p < 0.001) compared with conventional care. This study shows that the application of evidence‐based nursing in postoperative caesarean section care can effectively reduce the incidence of postoperative wound infection and complications and improve the quality of life, which is worthy of clinical nursing application and promotion.

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“…This increase in hospital visits may be caused by the delayed/deferred care in patients during the early months of pandemic and, therefore, increased the inpatient care visits with more complicated conditions [ 11 ]. This finding could also be associated with the cases of post-COVID-19 health complications and an increase of the adenovirus associated with acute appendicitis [ 35 , 36 ]. Several case reports have suggested a probable association between COVID-19 and subsequent acute appendicitis [ 36 ].…”

Section: Discussionmentioning

confidence: 99%

Impact of the COVID-19 Pandemic on the Pediatric Hospital Visits: Evidence from the State of Florida

Symum

Zayas‐Castro

2022

Pediatric Reports

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Although early evidence reported a substantial decline in pediatric hospital visits during COVID-19, it is unclear whether the decline varied across different counties, particularly in designated Medically Underserved Areas (MUA). The objective of this study is to explore the state-wide impact of COVID-19 on pediatric hospital visit patterns, including the economic burden and MUA communities. We conducted a retrospective observational study of pediatric hospital visits using the Florida State all-payer Emergency Department (ED) and Inpatient dataset during the pandemic (April–September 2020) and the same period in 2019. Pediatric Treat-and-Release ED and inpatient visit rates were compared by patient demographics, socioeconomic, diagnosis, MUA status, and hospital characteristics. Pediatric hospital visits in Florida decreased by 53.7% (62.3% in April–June, 44.2% in July–September) during the pandemic. The Treat-and-Release ED and inpatient visits varied up to 5- and 3-fold, respectively, across counties. However, changes in hospital visits across MUA counties were similar compared with non-MUA counties except for lower Treat-and-Release ED volume in April–May. The disproportional decrease in visits was notable for the underserved population, including Hispanic and African American children; Medicaid coverages; non-children’s hospitals; and diagnosed with respiratory diseases, appendicitis, and sickle-cell. Florida Hospitals experienced a USD 1.37 billion (average USD 8.3 million) decline in charges across the study period in 2020. Disproportionate decrease in hospital visits, particularly in the underserved population, suggest a combined effect of the persistent challenge of care access and changes in healthcare-seeking behavior during the pandemic. These findings suggest that providers and policymakers should emphasize alternative interventions/programs ensuring adequate care during the pandemic, particularly for high-risk children.

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Adenovirus-Associated Acute Appendicitis: An Under-Recognized Relationship?

Cited by 15 publications

References 13 publications

Association of meteorological factors with pediatric acute appendicitis in China

Association of meteorological factors with pediatric acute appendicitis in China

Impact of evidence‐based nursing on surgical site wound infection after caesarean: A meta‐analysis

Impact of the COVID-19 Pandemic on the Pediatric Hospital Visits: Evidence from the State of Florida

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