Adherence in Chronic Disease

Abstract

Nonadherence to treatmeot regimen is a prevalent problem of patients with chronic disorders. Approximately half of the patients with a chronic disease have problems following their prescribed regimen to the extent that they are unable to obtain optimum clinical benefit. This chapter reviews the state of knowledge regarding adherence to chronic disease regimens across the life span and demonstrates that the extent and nature of the adherence problems are similar across diseases, across regimens, and across age groups. Adherence to the commonly prescribed regimens is addressed, including pharmacological therapies, therapeutic diets, and therapeutic exercise. Randomized, controlled studies focusing on various educational, behavioral, cognitive, and affective interventions to improve adherence are included. Based on this review, further work is needed to better understand and improve adherence. New strategies for analysis and measurement will support these needed advances in the field of adherence.

Measuring treatment satisfaction in patients with primary immunodeficiency diseases receiving lifelong immunoglobulin replacement therapy

“…Failure to achieve sufficient treatment satisfaction may result from treatment side effects, lack of effectiveness or problems with treatment application. Low treatment satisfaction may in turn cause poor compliance, which further diminishes effectiveness, especially among patients with chronic diseases [22,26], and might eventually diminish patients' health-related quality of life (HRQL) [27].…”

Modelling the costs of care of hypertension in patients with metabolic syndrome and its consequences, in Germany, Spain and Italy

“…The treated group were then further sub-divided into three groups: those who continued with initial treatment for the full year (continuers), those who discontinued antihypertensive treatment within a year (discontinuers), and those who continued on antihypertensive treatment for the full year but switched from one treatment to another drug class (switchers). The continuation rate in the model was assumed to be 70%, which takes into account both the general poor adherence with long-term therapy [34] and the fact that the hypertensive population in the model will largely have established hypertension, with a smaller proportion being new users and re-starters (i.e. those previously discontinued but starting again).…”

Improving Collaborative Behaviour Planning in Adult Auditory Rehabilitation: Development of the I-PLAN Intervention Using the Behaviour Change Wheel

“…Behavioural problems like this are not unique to hearing healthcare. It is estimated that between a quarter and a half of patients with chronic disease have problems adopting and maintaining behaviour such as taking medication and following a diet or exercise plan [28,29].…”