Adherence in dermatology: A review of the last 20 years

Hodari, Kafele T.; Nanton, Jaleema R; Carroll, Christie L.; Feldman, Steven R.; Balkrishnan, Rajesh

doi:10.1080/09546630600688515

Cited by 73 publications

(81 citation statements)

References 27 publications

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“…The time, date and time elapsed since the bottle was last opened is recorded every time the cap is unscrewed. Provided the pharmaceutical formulation is suitable, the bottles can be used not only for solid and liquid, but also for semisolid presentation forms [34]. This monitoring system tends to furnish lower adherence values than the patient interview [35,36] or the determination of medication usage [32] and, consequently, is often regarded as today’s reference standard despite the costs and limited usage.…”

Section: Resultsmentioning

confidence: 99%

Adherence in the Treatment of Psoriasis: A Systematic Review

Augustin¹,

Holland²,

Dartsch

et al. 2011

Dermatology

146

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Background: Medication adherence and compliance are essential for disease management and can significantly improve outcomes and quality of patient care. The literature suggests that up to 40% of patients do not use their medication as intended. Objective: To elucidate current knowledge on adherence/compliance in psoriasis. In particular, methods of adherence/compliance evaluation and influencing factors were to be identified. Methods: Systematic literature review based on a protocol-rooted search in online databases, followed by a structured critical appraisal and consecutive descriptive report. Results: Thirty-five original publications on adherence/compliance in psoriasis were identified, addressing the extent and quality of adherence/compliance in topical, systemic and UV treatments. Estimates of compliance varied considerably between 27 and 97%. Age, sex, psychosocial, disease-specific and treatment-specific factors were identified as predictors of adherence/compliance. Conclusion: A better understanding of the determinants of adherence can improve the outcomes of psoriasis treatment and lead to higher patient satisfaction and quality of care.

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Section: Resultsmentioning

confidence: 99%

Adherence in the Treatment of Psoriasis: A Systematic Review

Augustin¹,

Holland²,

Dartsch

et al. 2011

Dermatology

146

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show abstract

“…4). The duration of treatment may also be of importance, since it has been shown that first-time users tend to be more adherent than patients who transitioned from previous therapies [27]. We did not see any differences in MPR between the patients who got their first biologic and the patients who were switched from another biologic.…”

Section: Discussionmentioning

confidence: 45%

“…Poor quality of life, depression, and resignation on part of the patient have a negative effect on compliance [27]. A positive attitude to medication can result in a measurable improvement of adherence [20].…”

Section: Discussionmentioning

confidence: 99%

Patient Adherence to Biologic Agents in Psoriasis

Hsu

Gniadecki²

2016

Dermatology

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Background: Low adherence to therapies in psoriasis decreases treatment outcomes and increases the total health care costs. In spite of the wide use of biologic agents, patients' adherence to these drugs has not been extensively investigated. Objective: The aim of this study is to measure adherence to the biologic drugs in a population of patients treated for psoriasis vulgaris using the medication possession ratio (MPR) index and to survey patients' attitudes to the treatment. Methods: This is a single-center study on 247 patients with psoriasis vulgaris treated with adalimumab (n = 113), etanercept (n = 39), and ustekinumab (n = 95). MPR calculation was calculated monthly based on the hospital records documenting the dispensing of biologics to the patients. Clinical data [Psoriasis Area and Severity Index (PASI), Dermatology Life Quality Index (DLQI), presence of psoriatic arthritis, concomitant treatment, and cause for treatment discontinuation] were obtained from the national database DERMBIO. Patients' attitudes and beliefs were measured using the Medication Adherence Rating Scale (MARS). Results: A total of 93.5% of all patients had an MPR ≥0.8, indicating very good adherence. MPR was independent of patients' age, gender, median PASI or DLQI score, concomitant diagnosis of psoriatic arthritis, or treatment with methotrexate. MPR for etanercept was slightly lower than that for ustekinumab and adalimumab. The MARS questionnaire documented satisfactory understanding of the treatment and its adverse effects, and positive attitudes to the treatment. Conclusion: Adherence to biologic therapies is very high in patients with psoriasis, which is consistent with a positive attitude to the treatment.

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“…Uma revisão de literatura sobre o tema mostrou que pouco se tem estudado sobre adesão em pacientes com dermatoses e um pequeno número de estudos encontrados que tratavam da utilização de tecnologia de monitoramento eletrônico mostrou que os pacientes dermatológicos apresentam baixas taxas de adesão aos regimes de tratamento, o que reforça a necessidade de intervenções para melhorar adesão. Existem fatores sócio-econômicos, emocionais e comportamentais que contribuem para a não-adesão, o que pode ser modificado com aumento do conhecimento do paciente sobre sua doença e sobre o tratamento, com uma boa relação médico-paciente (Hodari, Nanton, Carrol, Feldman & Balkrishnan, 2006) e também com intervenção psicológica .…”

Section: Intervenção Psicológicaunclassified

Avaliação da eficácia de um grupo psicoeducativo sobre ansiedade, depressão e qualidade de vida de pacientes com psoríase

Pavan-Cândido¹

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Adherence in dermatology: A review of the last 20 years

Cited by 73 publications

References 27 publications

Adherence in the Treatment of Psoriasis: A Systematic Review

Adherence in the Treatment of Psoriasis: A Systematic Review

Patient Adherence to Biologic Agents in Psoriasis

Avaliação da eficácia de um grupo psicoeducativo sobre ansiedade, depressão e qualidade de vida de pacientes com psoríase

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