Adherence of Pseudomonas aeruginosa to hydrophilic contact lenses and other substrata

Miller, Michael J.; Ahearn, Donald G.

doi:10.1128/jcm.25.8.1392-1397.1987

Cited by 110 publications

(26 citation statements)

References 23 publications

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“…Laboratory studies have demonstrated that Ps. aeruginosa will readily adhere to a variety of polymer surfaces [19,20]. This adherence and subsequent biofilm formation by micro-organisms is a common strategy for survival in natural ecosystems [21].…”

Section: Discussionmentioning

confidence: 99%

Epidemiology ofPseudomonas aeruginosakeratitis in contact lens wearers

et al. 1995

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This study evaluated the epidemiology of Pseudomonas aeruginosa keratitis in contact lens (CL) wearers; the relationships between CL storage case contamination and CL hygiene practice and between CL hygiene and the development of keratitis. Sixteen CL wearers with keratitis were compared with 44 asymptomatic controls. Lens hygiene practice was assessed and CL care materials, domestic water sites and endogenous sites were evaluated microbiologically. Poor CL hygiene was not associated with Ps. aeruginosa keratitis. There was an association between keratitis and bacterial contamination of the CL and storage case (P < 0.0005). Lens and storage case contamination were not significantly associated with poor hygiene. No domestic or endogenous source for Ps. aeruginosa was found. Causative organisms may be derived from other sources, but CLs and CL storage cases provide a favourable environment for Ps. aeruginosa colonization. Changing the CL care environment to one less favourable for Ps. aeruginosa may help to eliminate this problem.

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Section: Discussionmentioning

confidence: 99%

Epidemiology ofPseudomonas aeruginosakeratitis in contact lens wearers

et al. 1995

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“…Conversely, adhesion has been implicated as a possible virulence factor for several pathogenic microorganisms that are important in the medical, pharmaceutical, and food industries. Hydrophobic interactions have been associated with the adhesion of bacteria to surfaces in oral cavities (11,34), contact lenses (26), surgical and dental biomaterials (12,28), polymers targeted for food and pharmaceutical contact (39), and food (5).…”

mentioning

confidence: 99%

Hydrophobicity of Bacillus and Clostridium spores

Wiencek

Klapes

Foegeding

1990

Appl Environ Microbiol

137

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The hydrophobicities of spores and vegetative cells of several species of the genera Bacillus and Clostridium were measured by using the bacterial adherence to hexadecane assay and hydrophobic interaction chromatography. Although spore hydrophobicity varied among species and strains, the spores of each organism were more hydrophobic than the vegetative cells. The relative hydrophobicities determined by the two methods

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“…The materials employed to fabricate a contact lens influences the incidence of contact lens-associated microbial keratitis (12)(13)(14)(16)(17)(18)(19)(20). The type of polymers used in the manufacturing of contact lenses can enhance or interfere with bacterial adhesion.…”

Section: Discussionmentioning

confidence: 99%

“…Factors such as water content of lens material and surface hydrophobicity of bacteria are often exploited to limit bacterial contamination of contact lenses (13,15,21,22). Multiple studies have shown that there is an inverse relationship between bacterial adhesion and water content (15,(17)(18)(19)(21)(22)(23). The influence of surface hydrophobicity varies from strain to strain and can be altered depending on the suspension media.…”

Section: Discussionmentioning

confidence: 99%

Identification of Microorganisms Isolated From Counterfeit and Unapproved Decorative Contact Lenses

Land

Penno

Brzezinski

2017

Journal of Forensic Sciences

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All contact lenses (corrective/noncorrective) are considered Class II or Class III medical devices under the Federal Food, Drug, and Cosmetic Act, which also states that contact lenses can only be obtained with a prescription. The Forensic Chemistry Center of the US Food & Drug Administration has examined over 300 decorative, noncorrective contact lenses obtained without a prescription. Our observations indicate that 60% of the counterfeit lenses and 27% of the unapproved lenses examined were positive for microbial contamination. Twenty-nine different brands of noncorrective contact lenses were examined, and 48% of them had at least one sample positive for microbial contamination. Each microorganism was further identified using DNA sequencing. Contaminated contact lenses are associated with numerous health risks, including ocular infections and conjunctivitis leading to permanent visual impairment or blindness. These results support the contention that acquiring contact lenses without a prescription is a considerable threat to consumer health and safety.

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Adherence of Pseudomonas aeruginosa to hydrophilic contact lenses and other substrata

Cited by 110 publications

References 23 publications

Epidemiology ofPseudomonas aeruginosakeratitis in contact lens wearers

Epidemiology ofPseudomonas aeruginosakeratitis in contact lens wearers

Hydrophobicity of Bacillus and Clostridium spores

Identification of Microorganisms Isolated From Counterfeit and Unapproved Decorative Contact Lenses

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