2022
DOI: 10.1016/j.ijcha.2022.101092
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Adherence of ticagrelOr in real world patients with aCute coronary syndrome: The AD-HOC study

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“…This study will be the first trial dedicated to ACS patients, testing whether a DOAC-based dual approach is superior to a VKA-based triple approach in high-risk ACS patients with AF in terms of bleeding. In the context of combined APT and anticoagulant therapy however, Fiocca et al [22] raise the important issue of adherence to therapy. The Italian group assessed cessation patterns and causes of ticagrelor discontinuation in the AD-HOC (ADHerence of ticagrelOr in real-world patients with aCute coronary syndrome) cohort, and identified OAC as an independent predictor of premature ticagrelor cessation.…”
mentioning
confidence: 99%
“…This study will be the first trial dedicated to ACS patients, testing whether a DOAC-based dual approach is superior to a VKA-based triple approach in high-risk ACS patients with AF in terms of bleeding. In the context of combined APT and anticoagulant therapy however, Fiocca et al [22] raise the important issue of adherence to therapy. The Italian group assessed cessation patterns and causes of ticagrelor discontinuation in the AD-HOC (ADHerence of ticagrelOr in real-world patients with aCute coronary syndrome) cohort, and identified OAC as an independent predictor of premature ticagrelor cessation.…”
mentioning
confidence: 99%