Adherence to Anti-Hypertensive Medication and contributing factors among Non-Comorbid Hypertensive Patients in Two Hospitals of Jimma Town, South West Ethiopia.

Dego, Tolcha; Bobasa, Eshetu Mulisa

doi:10.5455/gulhane.1286

Cited by 5 publications

(34 citation statements)

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“…The full-text papers of 31 articles were retrieved and reviewed for inclusion which resulted in a total of 18 studies eligible for the methodological quality assessment. After excluding four studies with reasons mainly a weak quality score, 14 studies were included in the final SR (qualitative synthesis) [19][20][21][22][23][24][25][26][27][28][29][30][31][32] and 12 of them were also included in MA ( Figure 1).…”

Section: Selection Of the Studiesmentioning

confidence: 99%

“…Regarding the geographical part of the country, one study was conducted in the north, 19 four studies were in the northwest, 20,27,30,31 one study was in the northeast, 24 three studies were in the central, 26,29,32 two studies were in the western, 22,23 one study was in the southern, 28 and two studies were in the southwest. 21,25 Except for the study in Hawassa 28 which was an unmatched case-control study, all other studies were hospital-based cross-sectional quantitative in type. Except for the study in Adama, 29 the source population were adult hypertensive patients on antihypertensive medication for at least 1 month.…”

Section: Baseline Characteristics Of Studiesmentioning

confidence: 99%

“…Systematic random sampling was the main sampling technique which was used by six studies, 20,26,[28][29][30]32 , while six studies were included all adult hypertensive patients visiting the chronic follow-up clinic during data collection. 19,21,22,24,25,27 Face-to-face interviews with chart review were the main data collection technique used by eight studies 19 -21,23,25,26,28,30 while five studies 22,24,29,31,32 used interview (non-specific) technique and only one study 27 used self-administered questionnaires to assess adherence. The overview of the baseline characteristics of the 14 studies are presented in Table 1 (author, region, publication year, study design, study population, sample size, sampling technique, and data collection methods).…”

Section: Baseline Characteristics Of Studiesmentioning

confidence: 99%

“…Therapy-related factors. Eight studies reported significant associations between therapy-related factors and adherence to antihypertensive medications 21,[23][24][25]27,[30][31][32] (Table 5).…”

Section: Factors Associated With Adherencementioning

confidence: 99%

“…21 However, many studies revealed that medication adherence had no association with the number of pills patients took per day. 19,20,23,[25][26][27]30 A study in Addis Ababa reported that patients who are prescribed with two or less types of antihypertensive medications were three times (AOR = 3.17, 95% CI: 1.18-8.47) more likely to be adherent than those who took more than two types of medications. 32 A couple of studies reported that the duration of therapy was associated with antihypertensive medication adherence.…”

Section: Factors Associated With Adherencementioning

confidence: 99%

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Adherence to antihypertensive medications and associated factors among hypertensive patients in Ethiopia: Systematic review and meta-analysis

et al. 2020

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The foundation of controlling hypertension is adherence to antihypertensive medication adherence. This systematic review and meta-analysis aimed to assess the magnitude and associated factors of adherence to antihypertensive medication among adult hypertensive patients in Ethiopia. A comprehensible bibliographic searching was conducted from PubMed, EMBASE, Scopus, and Web of Science core collection. All published and unpublished studies that had been accessible before 31 May 2020, and written in English were eligible. Joanna Briggs Institute assessment tool was used to evaluate the quality of the findings of the included studies. Stata software 16.0 was used to analyze the data. Study-specific estimates were pooled to determine the overall prevalence estimate across studies using a random-effects meta-analysis model. Publication bias and heterogeneity were checked. Fourteen studies with a total of 4938 hypertensive patients were included in the final systematic review and meta-analysis. The pooled prevalence of medication adherence among hypertensive patients in Ethiopia was 65.41% (95% confidence interval: 58.91–71.91). Sub-group analysis shown that the pooled prevalence of medication adherence was the highest (69.07%, 95% confidence interval: 57.83–80.31, I2 = 93.51) among studies using questionnaire technique whereas the lowest in Morisky Medication Adherence Scale eight-items (60.66%, 95% confidence interval: 48.92–72.40, I2 = 97.16). Moreover, medication adherence was associated with the presence of comorbidities (pooled odds ratio = 0.23, 95% confidence interval: 0.07–0.38, p = 0.030, I2 = 54.9%) and knowledge about the disease and its management (pooled odds ratio = 2.98, 95% confidence interval: 1.72–4.24, p = 0.04, I2 = 55.55%) but not with place of residence (pooled odds ratio = 1.22, 95% confidence interval: 0.51–1.93, p = 0.00, I2 = 76.9%). Despite a lack of uniformity among included studies, adherence to antihypertensive medication among the hypertensive population in Ethiopia was moderate. The presence of comorbidities and/or complications reduced the odds of adherence whereas having good knowledge about the disease increased chance of medication adherence among hypertensive patients.

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Section: Selection Of the Studiesmentioning

confidence: 99%

Section: Baseline Characteristics Of Studiesmentioning

confidence: 99%

Section: Baseline Characteristics Of Studiesmentioning

confidence: 99%

Section: Factors Associated With Adherencementioning

confidence: 99%

Section: Factors Associated With Adherencementioning

confidence: 99%

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Adherence to antihypertensive medications and associated factors among hypertensive patients in Ethiopia: Systematic review and meta-analysis

et al. 2020

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Predictors of poor medication adherence of older people with hypertension

Wan

et al. 2022

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Medication adherence is defined as the degree to which a patient's behaviour corresponds to the agreed recommendations from a medical staff member. Good medication adherence is critical for maintaining the health of people, especially for chronic diseases (Asche et al., 2011;Han et al., 2014). Hypertension is a global public health problem, and it is the most important risk factor for all-cause mortality and disability worldwide (Collaborators, 2016). In 2010, hypertension was considered as a major risk factor for the global burden of disease (Lim et al., 2012). Studies have shown that controlled blood pressure may reduce 50% of cardiovascular events compared to uncontrolled blood pressure in people with hypertension (Kohlman-Trigoboff, 2016); thus, hypertension is a major modifiable risk factor

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Factors associated with poor medication adherence during COVID-19 pandemic among hypertensive patients visiting public hospitals in Eastern Ethiopia: a cross-sectional study

et al. 2022

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ObjectiveThis study aimed to assess factors associated with poor medication adherence during the COVID-19 pandemic among hypertensive patients visiting public hospitals in Eastern Ethiopia.SettingHospital-based cross-sectional study was conducted in Harari regional state and Dire Dawa Administration from 1 January to 30 February 2022. Both settings are found in Eastern Ethiopia.ParticipantsA total of 402 adult hypertensive patients who visited the chronic diseases clinic for follow-up were included in the study.Main outcome measuresThe main outcome measure was poor medication adherence during the COVID-19 pandemic.ResultsThe level of poor antihypetensive medication adherence was 63% (95% CI 48.1 to 67.9). Patients who had no formal education (adjusted OR (AOR)=1.56, 95% CI 1.03 to 4.30), existing comorbid conditions (AOR=1.98, 95% CI 1.35 to 4.35), self-funded for medication cost (AOR=2.05, 95% CI 1.34 to 4.73), poor knowledge about hypertension (HTN) and its treatment (AOR=2.67, 95% CI 1.45 to 3.99), poor patient–physician relationship (AOR=1.22, 95% CI 1.02 to 4.34) and unavailability of medication (AOR=5.05, 95% CI 2.78 to 12.04) showed significant association with poor medication adherence during the pandemic of COVID-19.ConclusionThe level of poor antihypertensive medication adherence was high in this study. No formal education, comorbidity, self-funded medication cost, poor knowledge about HTN and its treatment, poor patient–physician relationship, and unavailability of medication during the COVID-19 pandemic were factors significantly associated with poor adherence to antihypertensive medication. All stakeholders should take into account and create strategies to reduce the impact of the COVID-19 pandemic on medication adherence of chronic diseases.

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Adherence to Anti-Hypertensive Medication and contributing factors among Non-Comorbid Hypertensive Patients in Two Hospitals of Jimma Town, South West Ethiopia.

Cited by 5 publications

References 0 publications

Adherence to antihypertensive medications and associated factors among hypertensive patients in Ethiopia: Systematic review and meta-analysis

Adherence to antihypertensive medications and associated factors among hypertensive patients in Ethiopia: Systematic review and meta-analysis

Predictors of poor medication adherence of older people with hypertension

Factors associated with poor medication adherence during COVID-19 pandemic among hypertensive patients visiting public hospitals in Eastern Ethiopia: a cross-sectional study

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