Adherence to antihypertensive drug treatment in Argentina: A multicenter study

Espeche, Walter G; Salazar, Martín R.; Sabio, Rodrigo; Díaz, Alejandro; Sisnieguez, Carlos Enrique Leiva; Olano, D.; Balbín, Eduardo; Renna, Nicolás Federico; Grosse, Pedro; Flores, Roberto A.; Lagos, Ana Catarina; Ferrer, P.; Poppe, Silvia; Patron, F. Risso; Stasiuk, Victor D. Sotnieczuk; Valentini, Elina; Cardozo, Jose R.; Romano, José; Parodi, Roberto; Carbajal, Horacio A

doi:10.1111/jch.13830

Cited by 9 publications

(9 citation statements)

References 22 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Adherence : MMAS-8 will be trichotomized into three levels of adherence as that was done to facilitate its use in clinical practice: high adherence (MMAS score of 8); medium adherence (MMAS scores of 6 to < 8), and low adherence (MMAS scores of <6) [ 27 , 28 ]. Non-adherence was considered when MMAS score <8.…”

Section: Methodsmentioning

confidence: 99%

“…An eight item Morisky’s Medication Adherence Scale (MMAS-8) was employed to assess the study participant’s medication adherence [ 27 ]. A scoring scheme of “Yes” = 0 and “No” = 1 for the first seven items except item number five in which the values are of “Yes” and “No” are reversed and for the last item a five-point Likert response are used with options “never”, “once in a while”, “sometimes”, “usually”, and “always” [ 28 ]. A BP value of participants, which has been measured recently, was used to assess whether BP is controlled or not.…”

Section: Methodsmentioning

confidence: 99%

See 1 more Smart Citation

Medication regimen complexity and its association with adherence and blood pressure control among hypertensive patients at selected hospitals of South Gondar Zone: A hospital based cross sectional study

et al. 2022

View full text Add to dashboard Cite

Introduction Despite the availability of effective antihypertensive medications, blood pressure (BP) control is suboptimal. High medication regimen complexity index (MRCI) is known to reduce adherence and may be the reason for poor BP control. However, there is no data in the present study areas. Hence, the aim of this study was to assess MRCI and its association with adherence and BP control among hypertensive patients at selected hospitals of South Gondar Zone. Methods A hospital based cross sectional study was conducted from December 1, 2020 to February 30, 2021 at selected hospitals of South Gondar Zone. Medication regimen complexity and adherence was evaluated using 65-item validated tool called MRCI and eight items Morisky Medication Adherence, respectively. Multivariable logistic regression analysis was done to determine the association between predictive and outcome variables. Results About 3.3% of participants were classified as having high HTN specific MRCI whereas 34.75% of participants were classified as having high patient level MRCI. Among participants, 37.8% were adherent to their medications, and 52.2% of respondents were categorized as having controlled BP. Multivariate logistic regression showed being married, and having lower education level was more likely and less likely to be adherent, respectively. Being illiterate, and having low HTN MRCI were more likely to have controlled BP in adjusted analyses. On the contrary, being non-adherent, not having health insurance, and having lower monthly income were less likely to have controlled BP. Conclusion A considerable proportion of patients had high MRCI. Having low HTN MRCI was more likely to have controlled BP. Simplification of a complex medication regimen for patients with HTN should be sought by physicians and pharmacists to improve BP control.

show abstract

Section: Methodsmentioning

confidence: 99%

Section: Methodsmentioning

confidence: 99%

Medication regimen complexity and its association with adherence and blood pressure control among hypertensive patients at selected hospitals of South Gondar Zone: A hospital based cross sectional study

et al. 2022

View full text Add to dashboard Cite

show abstract

“…Interestingly, high educational level was an independent and strong predictor for high adherence. 13 Patient adherence to therapy can be improved by several interventions and multicomponent interventions could have a greater effect on adherence, as the effect size of each intervention is generally modest.…”

Section: Salazarmentioning

confidence: 99%

“…These patients had lower BP values and higher control levels. Interestingly, high educational level was an independent and strong predictor for high adherence 13 …”

mentioning

confidence: 95%